Human DR (Ia-like) antigens: biological and molecular profile.
Human DR (Ia-like) antigens: biological and molecular profile.
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人类 DR（Ia 样）抗原：生物学和分子特征。
DOI：
10.1007/978-1-4757-0779-3_8
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发表时间：
1978
期刊：
影响因子：
--
通讯作者：
M. A. Pellegrino
中科院分区：
文献类型：
--
作者：
Soldano Ferrone;James P. Allison;M. A. Pellegrino
免疫系统细胞的功能可能是通过特定的表面大分子介导的。虽然已知特定的细胞表面标记与淋巴细胞的各种功能不同的亚群有关，但这些标记在淋巴细胞亚类的特定功能中的作用仍有待确定。在免疫生物学中，当前的热门话题之一是细胞表面标记物的分子和结构表征，这些标记物可能介导免疫细胞的特定功能。最终，这些研究将揭示这些细胞特殊功能的分子基础，并将允许每种功能与可识别的细胞表面结构的相关性。
The functions that a cell of the immune system performs may be mediated through particular surface macromolecules. Although specific cell-surface markers are known to be associated with various functionally distinct subpopulations of lymphocytes, the role of these markers in the specific functions of subclasses of lymphocytes remains to be defined. In immunobiology, one of the current “hot” topics is the molecular and structural characterization of cell-surface markers that may mediate specific functions of immune cells. Ultimately, such studies will disclose the molecular basis of these cells’ specialized functions and will allow the correlation of each function with an identifiable cell-surface structure.