Stroke in Women and Unique Risk Factors.
Stroke in Women and Unique Risk Factors.
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女性中风和独特的危险因素。
DOI：
10.1161/strokeaha.122.041734
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发表时间：
2023
期刊：
影响因子：
8.3
通讯作者：
Kapral,MoiraK
中科院分区：
文献类型：
--
作者：
Bushnell,CherylD;Kapral,MoiraK
在过去的一年里，有大量的研究集中在女性特有的风险因素和中风的性别差异上。本文总结了一些新的研究，提供了新的知识领域的中风妇女。护士健康研究II提供了腹腔镜证实的子宫内膜异位症与未来卒中之间关系的新数据，解释了子宫切除术和卵巢切除术的中介作用。在一个中国女性队列中，子宫切除术、卵巢切除术和卒中之间的关系得到了进一步的阐明，说明了手术的年龄。英国生物银行的研究提供了关于口服避孕药和激素替代疗法与中风之间关系的新信息，分析技术侧重于与暴露持续时间相关的事件发生时间。最后，2项新的荟萃分析探讨了卒中症状的表现是否存在性别差异。
There has been a plethora of studies focused on female-specific risk factors and sex differences in stroke published in the past year. This article summarizes several of those novel studies which provide new knowledge about the field of stroke in women. The Nurses’ Health Study II provides new data on the association between laparoscopically proven endometriosis and future stroke, accounting for the mediation effects of hysterectomy and oophorectomy. In a cohort of women from China, the relationship between hysterectomy, oophorectomy, and stroke is further clarified, accounting for the age at which the procedure is performed. The UK Biobank study provides new information on the relationship between oral contraceptive and hormone replacement therapy and stroke, with analytical techniques that focus on the timing of events related to duration of exposure. Finally, 2 new meta-analyses address the question of whether sex differences exist in the presentation of stroke symptoms.