NATURAL-HISTORY OF EXTRAMEDULLARY PLASMACYTOMA AND ITS RELATION TO SOLITARY MYELOMA OF BONE AND MYELOMATOSIS

NATURAL-HISTORY OF EXTRAMEDULLARY PLASMACYTOMA AND ITS RELATION TO SOLITARY MYELOMA OF BONE AND MYELOMATOSIS
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DOI:
10.1097/00005792-197605000-00002
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发表时间:
1976-01-01
期刊:
影响因子:
1.6
通讯作者:
WILTSHAW, E
WILTSHAW, E
中科院分区:
医学4区
文献类型:
--
作者:
WILTSHAW, E

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骨髓瘤病、骨单发骨髓瘤和髓外浆细胞瘤之间的相互关系尚不清楚,普遍的观点是它们仅仅代表一种肿瘤的变异谱(6,21,27,38)。这种观点的产生部分是由于缺乏术语定义,部分是由于对骨髓瘤病髓外受累程度的误解(13,25)。本文的目的是阐明髓外浆细胞瘤与其他浆细胞肿瘤的关系。我自己的研究表明,髓外浆细胞瘤具有与骨髓瘤病不同的特征,但骨孤立性骨髓瘤似乎是骨髓瘤病的一种罕见发病模式。
The interrelationship of myelomatosis, soli-tary myeloma of bone and extramedullary plas-macytoma is not well understood, and the prevalent idea is that they represent no more than a spectrum of variation of one tumor (6, 21, 27, 38). This idea has arisen partly through a lack of definition of terms and partly through a misconception of the degree of extramedullary involvement in myelomatosis (13, 25). The purpose of this paper is to clarify the position of extramedullary plasmacytoma in relation to other plasma-cell tumors. My own studies have shown that extramedullary plasmacytoma has characteristic features which distinguish it from myelomatosis, but that solitary myeloma of bone appears to be a rare mode of onset of myelomatosis.