The longitudinal study of the northern Finland birth cohort of 1966.

The longitudinal study of the northern Finland birth cohort of 1966.
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DOI:
10.1111/j.1365-3016.1988.tb00180.x
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发表时间:
1988-01-01
影响因子:
2.8
通讯作者:
Rantakallio, P
Rantakallio, P
中科院分区:
医学3区
文献类型:
--
作者:
Rantakallio, P

文献摘要

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1966年,芬兰北方的出生队列包括12 058名活产婴儿,占该地区所有出生婴儿的96.3%。调查在怀孕期间开始,整个系列的最后一次随访是在14岁时,当时覆盖面仍然很大。还对较小的儿童样本和来自国家登记册的研究人口数据进行了检查,以了解年龄较大的群体。研究了儿童的健康和发育,特别强调获得可靠的神经障碍发生率数据及其与围产期事件的相关性。特别是,低出生体重和障碍条件之间的相关性被彻底记录。在母亲的生物学特征和母亲及家庭的社会条件中,预测低出生体重的指标包括母亲在怀孕期间吸烟。后者不仅与不良围产期结局有关,而且与幸存者的教育成就和身高下降有关。
The Northern Finland birth cohort comprises 12,058 live births in 1966-96.3% of all births in the region. The investigation was started during pregnancy and the last follow-up of the total series was at the age of 14 years, when the coverage was still large. Smaller samples of the children and data for the study population from national registers were also examined for the older age groups. The health and development of the children was studied, with special emphasis placed on obtaining reliable incidence figures for neurological handicaps and their correlation with perinatal events. In particular, the correlation between low birthweight and handicapping conditions was documented thoroughly. The indicators predictive of low birthweight among the biological characteristics of the mother and the social conditions of the mother and family, included maternal smoking during pregnancy. The latter was associated not only with adverse perinatal outcome but also with reduction in educational achievement and height among survivors.