Stromal lenticule transplantation for management of corneal perforations; one year results
Stromal lenticule transplantation for management of corneal perforations; one year results
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DOI：
10.1007/s00417-017-3645-6
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发表时间：
2017-06-01
影响因子：
2.7
通讯作者：
El SaebaySarhan, Abdel Rahman
中科院分区：
文献类型：
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作者：
Elaziz, Mohamed Samy Abd;Zaky, Adel Galal;El SaebaySarhan, Abdel Rahman
目的：探讨飞模激光小切口晶状体提取术（SMILE）间质晶状体作为角膜穿孔的手术辅助手段的应用。通过SMILE手术获得中心厚度为100 μ m或更大的角膜间质透镜，使用10-0尼龙间断针和单层羊膜将其固定在角膜穿孔部位。随访至少12个月的7例患者采用裂隙灯生物显微镜、荧光素染色、血压计和最佳眼镜矫正视力（BSCVA）测量进行评估。随访期间记录术后并发症。7例患者均成功封闭角膜穿孔；术后BSCVA改善3例（42.9%）。在一年的随访期间，没有发现任何患者出现再穿孔或感染的迹象。这些早期研究结果表明，角膜间质皮泡作为一种安全有效的角膜穿孔闭合辅助手术，与羊膜一起作为一种相对简单和低成本的临时措施，为进一步的确定手术做准备，具有潜在的临床应用价值。
To study application of stromal lenticules extracted by femtolaser small incision lenticule extraction (SMILE) surgery as a surgical adjuvant to seal corneal perforations.Corneal stromal lenticules obtained through SMILE surgery with central thickness 100 mu m or more were fixed over corneal perforation sites using 10-0 nylon interrupted stitches with an overlying single layer of amniotic membrane. Seven patients who had been followed up for a minimum of 12 months were assessed using slit-lamp biomicroscopy, fluorescein stain, tonometry, and best spectacle-corrected visual acuity (BSCVA) measurements. Postoperative complications were recorded throughout the follow up period.Corneal perforations had successfully been sealed in all 7 patients; 3 patients (42.9%) exhibited improved postoperative BSCVA. During the follow-up period of one year, no signs of re-perforation or infections were detected in any patient.These early findings suggest that the use of corneal stromal lenticules could be a safe and efficient surgical adjuvant for corneal perforation closure with potential clinical application, together with amniotic membrane, as relatively simple and low cost temporary measures to prepare perforated corneas for further definitive procedures.