Speed of sound in bone at the tibia: is it related to lower limb bone mineral density in spinal-cord-injured individuals?
Speed of sound in bone at the tibia: is it related to lower limb bone mineral density in spinal-cord-injured individuals?
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DOI：
10.1038/sj.sc.3101570
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发表时间：
2004-03-01
期刊：
影响因子：
2.2
通讯作者：
Webber, CE
中科院分区：
文献类型：
--
作者：
Giangregorio, LM;Webber, CE
Study design: A cross-sectional study evaluating BMD at the hipand tibia, and SOS at the radius and mid-tibia in individuals with spinal cord injury (SCI) and a subgroup of non-SCI individuals.Objectives: To investigate the speed of sound ( SOS) in bone in relation to bone mineral density ( BMD). Setting: Kinesiology Department, McMaster University, Ontario, Canada.Methods: In 14 individuals with SCI and 10 non-SCI individuals, proximal femur and tibia BMD were measured using dual energy X-ray absorptiometry, and radius and tibia SOS were measured with an ultrasonometer. T-scores were calculated using healthy reference databases. Inter-relationships between measurement techniques were determined using Pearson's correlation coefficients. P-values less than 0.05 were considered statistically significant.Results: The average ages of the SCI and non-SCI groups were 33 +/- 9 and 27 +/- 6 years, respectively. Lesion level ranged from C4 to T12 and average time postinjury was 12 years, with a range of 1.6 - 25 years. Using the WHO criteria for osteoporosis, nine of 14 SCI subjects were osteoporotic at the hip, with the remainder in the osteopenic range. Tibia SOS T-scores were in the osteoporotic range for one subject with SCI, and two were in the osteopenic range. Among non-SCI individuals, one male had a tibia SOS T-score of - 1.4, all others were within the normal range. Hip BMD and tibia SOS were significantly correlated ( r = 0.46, P
