FRACTION DEPENDENT VARIATION OF ASPARTIC-ACID RACEMIZATION AGE OF FOSSIL BONE
FRACTION DEPENDENT VARIATION OF ASPARTIC-ACID RACEMIZATION AGE OF FOSSIL BONE
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DOI：
10.1038/286883a0
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发表时间：
1980-01-01
期刊：
影响因子：
64.8
通讯作者：
UETA, N
中科院分区：
文献类型：
--
作者：
MATSUURA, S;UETA, N
氨基酸外消旋化的程度为各种化石材料的年代学提供了有价值的信息1 -3。在骨骼中，天冬氨酸受到了最多的关注，这种氨基酸的D/L比率已被用于估计人类骨骼肌的年龄4 -9。然而，这些估计值是基于对可能以各种形式（即蛋白质、肽和游离氨基酸）存在的总残留天冬氨酸测定的外消旋化程度。讨论了氨基酸化学状态对钙质海洋沉积物10和贝壳11中氨基酸外消旋速率或年龄的影响。在骨骼中，加热的现代样品中的不可透析材料（异亮氨酸）的外消旋化率低于总有机基质12;化石骨骼中的游离氨基酸比结合（盐酸不溶性）氨基酸的外消旋化率更高13。本研究的目的是评估这种波动的天冬氨酸外消旋年龄为一个给定的骨标本所造成的变异性的形式，其中存在的氨基酸。
The extent of racemization of amino acids provides valuable information on the chronology of various fossil materials1–3. In bone, aspartic acid has received the most attention, and the D/L ratio of this amino acid has been used to estimate ages of human skeletal remains4–9. These estimates were, however, based on the degree of racemization determined for total remnant aspartic acid which may exist in various forms (that is, protein, peptide and free amino acid). The effect of the chemical state of amino acids on amino acid racemization rates or ages in calcareous marine sediments10and shells11has been discussed. In bones, the non-dialysable material in a heated modern sample has a lower racemization rate (isoleucine) than the total organic matrix12; free amino acids in fossil bone are more highly racemized than are bound (HCl-insoluble) amino acids13. The present investigation was designed to assess such fluctuation of aspartic acid racemization age for a given bone specimen as caused by the variability of the form in which the amino acid is present.