The peroxisome proliferator-activated receptor gamma agonist pioglitazone prevents NF-kappaB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway.
The peroxisome proliferator-activated receptor gamma agonist pioglitazone prevents NF-kappaB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway.
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过氧化物酶体增殖物激活受体 γ 激动剂吡格列酮通过 AMPK-SIRT1/p300 途径减少 p65 乙酰化,从而防止顺铂肾毒性中 NF-kappaB 的激活。
DOI:
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发表时间:
2016
期刊:
影响因子:
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通讯作者:
Xu, Gang
中科院分区:
文献类型:
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作者:
Rong, Song;Yao, Ying;Li, Junhua;Xu, Gang