Vagovagal reflex control of digestion: afferent modulation by neural and "endoneurocrine" factors.

Vagovagal reflex control of digestion: afferent modulation by neural and "endoneurocrine" factors.
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DOI:
10.1152/ajpgi.1995.268.1.g1
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发表时间:
1995
期刊:
The American journal of physiology
影响因子:
--
通讯作者:
R. Rogers;D. McTigue;G. Hermann
R. Rogers;D. McTigue;G. Hermann
中科院分区:
其他
文献类型:
--
作者:
R. Rogers;D. McTigue;G. Hermann

文献摘要

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脑干背侧迷走神经复合体中的迷走神经反射控制回路提供胃、小肠和胰腺消化功能的整体协调。形成这些反射回路的神经组件受到显着的下行神经控制。通过调整反射不同部分的兴奋性,中枢神经系统可以显着改变消化控制。此外,背侧迷走神经复合体位于心室周围区域内,没有“血脑屏障”。因此,迷走神经反射回路也受到体液的影响,体液可以通过直接作用于脑干神经元来深刻改变消化功能。
Vagovagal reflex control circuits in the dorsal vagal complex of the brain stem provide overall coordination of gastric, small intestinal, and pancreatic digestive functions. The neural components forming these reflex circuits are under substantial descending neural control. By adjusting the excitability of the differing components of the reflex, significant alterations in digestion control can be produced by the central nervous system. Additionally, the dorsal vagal complex is situated within a circumventricular region without a "blood-brain barrier." As a result, vagovagal reflex circuitry is also exposed to humoral influences, which can profoundly alter digestive functions by acting directly on brain stem neurons.