Phylogeographic patterning of mtDNA in the widely distributed harvest mouse (Micromys minutus) suggests dramatic cycles of range contraction and expansion during the mid- to late Pleistocene
Phylogeographic patterning of mtDNA in the widely distributed harvest mouse (Micromys minutus) suggests dramatic cycles of range contraction and expansion during the mid- to late Pleistocene
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DOI：
10.1139/z05-139
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发表时间：
2005-11-01
影响因子：
1.4
通讯作者：
Suzuki, H
中科院分区：
文献类型：
--
作者：
Yasuda, SP;Vogel, P;Suzuki, H
我们研究了欧亚收获鼠（Micromys minutus（Pallas，1771））线粒体细胞色素B基因（1140 bp，n = 73）和控制区（842-851 bp，n = 74）的序列变异，从西欧到日本。系统地理学分析显示，区域特定的单倍型分组与整体水平低的区域间遗传分化相结合。尽管存在巨大的间隔距离，但欧洲和东亚样本的净核苷酸差异仅为0.36%。基于细胞色素B基因2.4%的进化率（.）（site）lineage（.）（-1），这些种群的初始分化时间估计在距今约80000年前。我们的发现与现有的化石证据相一致，这些证据记录了M. minutus通过第四纪。分子数据进一步表明，在中亚至东亚地区的避难所发生的Escherichiogenization。日本M.小的，除了那些从对马群岛，与邻近的朝鲜半岛相比，显示有限的核苷酸多样性（0.15%）。这一发现表明日本列岛最近的殖民化，可能是在最后一个冰川时期，随后人口迅速增长。
We examined sequence variation in the mitochondrial cytochrome b gene (1140 bp, n = 73) and control region (842-851 bp, n = 74) in the Eurasian harvest mouse (Micromys minutus (Pallas, 1771)), with samples drawn from across its range, from Western Europe to Japan. Phylogeographic analyses revealed region-specific haplotype groupings combined with overall low levels of inter-regional genetic divergence. Despite the enormous intervening distance, European and East Asian samples showed a net nucleotide divergence of only 0.36%. Based on an evolutionary rate for the cytochrome b gene of 2.4%(.)(site(.)lineage(.)million years)(-1), the initial divergence time of these populations is estimated at around 80 000 years before present. Our findings are consistent with available fossil evidence that has recorded repeated cycles of extinction and recolonization of Europe by M. minutus through the Quaternary. The molecular data further suggest that recolonization occurred from refugia in the Central to East Asian region. Japanese haplotypes of M. minutus, with the exception of those from Tsushima Is., show limited nucleotide diversity (0.15%) compared with those found on the adjacent Korean Peninsula. This finding suggests recent colonization of the Japanese Archipelago, probably around the last glacial period, followed by rapid population growth.