Magnetoencephalography identifies rapid temporal processing deficit in autism and language impairment
Magnetoencephalography identifies rapid temporal processing deficit in autism and language impairment
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DOI：
10.1097/00001756-200503150-00005
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发表时间：
2005-03-15
期刊：
影响因子：
1.7
通讯作者：
Roberts, TPL
中科院分区：
文献类型：
--
作者：
Cardy, JEO;Flagg, EJ;Roberts, TPL
缺乏快速的时间处理可能会导致语言发育受损，干扰短暂的声音转换的处理至关重要的言语感知。本文应用脑磁图技术，记录了10名正常成人和40名8-17岁孤独症、特殊语言障碍、Fredger综合征或典型发育儿童对两个40 ms短声连续快速被动诱发的诱发神经活动（M50，M100）。虽然80%的语言完整的研究参与者（典型发育，成年人）对第二个音调表现出可识别的反应，这表现出快速的时间处理需求，但65%的语言受损的研究参与者（自闭症，特定语言障碍）没有，尽管对第一个音调表现出可识别的反应。快速时间处理障碍可能从根本上与语言障碍有关，而不是自闭症谱系障碍。NeuroReport 16：329-332（c）2005 Lippincott威廉姆斯和威尔金斯。
Deficient rapid temporal processing may contribute to impaired language development by interfering with the processing of brief acoustic transitions crucial for speech perception. Using magnetoencephalography, evoked neural activity (M50, M100) to two 40 ms tones passively presented in rapid succession was recorded in 10 neurologically normal adults and 40 8-17-year-olds with autism, specific language impairment, Asperger syndrome or typical development. While 80% of study participants with intact language (Asperger syndrome, typical development, adults) showed identifiable responses to the second tone, which presented rapid temporal processing demands, 65% of study participants with impaired language (autism, specific language impairment) did not, despite having shown identifiable responses to the first tone. Rapid temporal processing impairments may be fundamentally associated with impairments in language rather than autism spectrum disorder. NeuroReport 16:329-332 (c) 2005 Lippincott Williams & Wilkins.