STRUCTURAL AND ENZYMATIC PROPERTIES OF CALCIUM TRANSPORTING MEMBRANES OF SARCOPLASMIC RETICULUM
STRUCTURAL AND ENZYMATIC PROPERTIES OF CALCIUM TRANSPORTING MEMBRANES OF SARCOPLASMIC RETICULUM
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DOI：
10.1111/j.1749-6632.1966.tb50216.x
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发表时间：
1966-01-01
影响因子：
5.2
通讯作者：
HASSELBA.W
中科院分区：
文献类型：
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作者：
HASSELBA.W
M，活纤维和提取纤维中的可收缩蛋白都不会与ATP发生酶反应，也不会收缩。（Weber & Herz, 1963; Portzehl et al., 1964）。可收缩的蛋白质处于松弛状态。肌动蛋白和肌凝蛋白丝分离。将钙添加到分离的蛋白质中或注射到活纤维中，可诱导收缩和肌动球蛋白atp酶活性。当钙浓度达到5 × M时，两种情况下均发生阈值收缩（图1）（Heilbrunn & Wiercinsky, 1947; Portzehl et a）。, 1964)。3. 使分离的可收缩蛋白饱和以达到最大活性所需的钙量相当于每个肌球蛋白分子一个钙离子
M, neither the contractile proteins in the living fibers, as well as in the extracted fibers, react enzymatically with ATP nor do they contract.(Weber & Herz, 1963; Portzehl et al., 1964). The contractile proteins are in the relaxed state. Actin and myosin filaments are dissociated.2. Contraction and Actomyosin ATPase activity are induced when calcium is added to the isolated proteins or injected into the living fiber. Threshold contractions occur in both cases when the calcium level reaches 5 X M (FIG-URE 1)(Heilbrunn & Wiercinsky, 1947; Portzehl et a]., 1964). 3. The amount of calcium required to saturate the isolated contractile proteins for maximal activity corresponds to one calcium ion per myosin molecule