Vaccination Response to an Ongoing Meningitis Outbreak: Uptake and Attitudes among Men Who Have Sex with Men in Los Angeles, CA
Vaccination Response to an Ongoing Meningitis Outbreak: Uptake and Attitudes among Men Who Have Sex with Men in Los Angeles, CA
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DOI：
10.1093/ofid/ofx163.1046
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发表时间：
2017-10-04
影响因子：
4.2
通讯作者：
Frew P
中科院分区：
文献类型：
--
作者：
Holloway I;Wu E;Gildner J;Fenimore V;Frew P
男男性行为者（MSM）是侵袭性脑膜炎球菌病（IMD）的高危人群。在2016年IMD在南加州爆发后，公共卫生官员发布了一项建议，敦促有风险的成年同性恋和双性恋男子以及所有艾滋病毒感染者接种疫苗。尽管公共卫生部门努力提高MCV 4的覆盖率，但MSM的吸收和接受程度仍然未知。因此，我们的研究试图：（1）估计加利福尼亚州洛杉矶MSM中报告的MCV 4免疫接种;（2）记录最近爆发后最新疫苗接种建议的促进因素和障碍。从2016年11月到2017年2月，我们使用基于场地的抽样方法在洛杉矶招募MSM（N = 513）。符合条件的参与者完成了一项30分钟的iPad调查，其中包括MCV 4状态，性行为，疫苗接种知识和行为等因素。卡方检验和独立样本t检验用于确定双变量相关性。来自双变量分析的统计学显著变量被包括在预测MCV 4摄取的多变量逻辑回归模型中。参与者为年轻人（M=33，SD=10），种族/民族多样：白色（35.7%）、黑人/非裔美国人（14.6%）、西班牙裔（36.5%）、亚洲/太平洋岛民（4.1%）、其他（9.2%）。报告的男男性行为者（25.4%）和感染艾滋病毒的男男性行为者（37.7%）MCV 4免疫率较低。在我们的多变量模型中，MCV 4摄取的统计学显著相关性包括：年龄较小（aOR = 2.51），既往STI诊断（aOR=2.21），认为MCV 4疫苗接种很重要（aOR=3.45），对MCV 4疫苗有信心（aOR=5.43），以及知道有人接受过疫苗接种（aOR=5.79）。MSM的感知健康风险，疫苗的信心，并接受MCV 4疫苗的人的知识是脑膜炎免疫接种在这次疫情的重要指标。通过强调个人健康风险、MCV 4的安全性和有效性以及脑膜炎球菌疫苗对男性健康的重要性的信息，可以加强提供者和公共卫生教育工作。由接种过疫苗的人促进的流行意见领袖计划有必要提高MCV 4的摄取。 所有作者：无报告披露。
Men who have sex with men (MSM) are at high risk for invasive meningococcal disease (IMD). Following a 2016 IMD outbreak in Southern California, public health officials issued an advisory that urged at-risk adult gay and bisexual men, and all people with HIV, to obtain immunizations. Despite public health efforts to increase MCV4 coverage, uptake and acceptance among MSM remains unknown. Thus, our study sought to: (1) estimate reported MCV4 immunization among MSM in Los Angeles, CA; and (2) document the facilitators and barriers to the newest vaccination recommendation following the recent outbreak. From November 2016 through February 2017, we used venue-based sampling to recruit MSM in Los Angeles (N = 513). Eligible participants completed a 30-minute iPad survey that included items on MCV4 status, sexual behavior, vaccination knowledge and behaviors among other factors. Chi-square and independent sample t-tests were used to determine bivariate associations. Statistically significant variables from bivariate analyses were included in a multivariate logistic regression model predicting MCV4 uptake. Participants were young (M=33, SD=10) and racially/ethnically diverse: White (35.7%), Black/African American (14.6%), Hispanic (36.5%), Asian/Pacific Islander (4.1%), Other (9.2%). Reported MCV4 immunization among MSM (25.4%) and MSM living with HIV (37.7%) was low. Statistically significant correlates of MCV4 uptake in our multivariate model included: younger age (aOR=2.51), prior STI diagnosis (aOR=2.21), believing MCV4 vaccination was important (aOR=3.45), having confidence in the MCV4 vaccine (aOR=5.43), and knowing someone who had received the vaccination (aOR=5.79). MSM’s perceived health risk, vaccine confidence, and knowledge of someone who received the MCV4 vaccine were important indicators of meningitis immunization in this outbreak context. Provider and public health education efforts may be enhanced by messages that emphasize personal health risks, the safety and efficacy of MCV4, and the importance of meningococcal vaccines for men’s health. Popular opinion leader programs facilitated by someone who had been vaccinated are warranted to enhance MCV4 uptake. All authors: No reported disclosures.