Effects of momentum-based dumbbell training on cognitive function in older adults with mild cognitive impairment: a pilot randomized controlled trial.

Effects of momentum-based dumbbell training on cognitive function in older adults with mild cognitive impairment: a pilot randomized controlled trial.
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基于动量的哑铃训练对轻度认知障碍老年人认知功能的影响:一项随机对照试验

DOI:
10.2147/cia.s96042
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发表时间:
2016
影响因子:
3.6
通讯作者:
Liu Y
Liu Y
中科院分区:
医学2区
文献类型:
--
作者:
Lü J;Sun M;Liang L;Feng Y;Pan X;Liu Y

文献摘要

被引文献

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本研究的目的是探讨一种创新的动量哑铃训练干预对老年轻度认知障碍(MCI)患者认知功能的影响。共有45名社区居住的MCI老年人被随机分配到哑铃训练组(DTG; n=22)或对照组(CG; n=23)。DTG的参与者每周参加三次锻炼,持续12周。主要结局指标为认知功能,包括阿尔茨海默病评估量表(ADAS)-认知子量表、连线测试部分B、数字广度测试(DST)-正向和DST -反向,次要结局指标为计时启动和启动、功能范围和活动特异性平衡信心量表。在意向治疗分析中,与CG组相比,DTG组的参与者ADAS -认知子量表评分显著改善(5.02分,P=0.012)。连线测验部分B(33.32秒,P<0.001)和DST -后向(0.41分,P=0.025)评分有显著的组内变化(改善)。DST -远期测量未观察到变化。与CG组相比,DTG组的参与者也改善了他们的功能活动性(计时起身和行走,0.81秒; P=0.043)。有初步证据表明,动量哑铃训练对改善MCI老年人的认知功能有潜在益处。
The purpose of this study was to explore the effects of an innovative momentum-based dumbbell-training intervention on cognitive function in older adults with mild cognitive impairment (MCI). A total of 45 community-dwelling older adults with MCI were randomly assigned to either a dumbbell-training group (DTG; n=22) or a control group (CG; n=23). Participants in the DTG participated in exercise sessions three times weekly for 12 weeks. The primary outcome measures were cognitive function, including the Alzheimer’s Disease Assessment Scale (ADAS) – Cognitive subscale, Trail Making Test part B, Digit Span Test (DST) – forward, and DST – backward, with secondary outcome measures being Timed Up and Go, functional reach, and the Activities-Specific Balance Confidence Scale. In an intent-to-treat analysis, participants in the DTG had significantly improved ADAS – Cognitive subscale scores compared to those in the CG (5.02 points, P=0.012). There was a significant within-group change (improvement) in Trail Making Test part B (33.32 seconds, P<0.001) and DST – backward (0.41 points, P=0.025) scores. No change was observed for the DST – forward measure. Participants in the DTG also improved their functional mobility compared to those in the CG (Timed Up and Go, 0.81 seconds; P=0.043). There is preliminary evidence showing the potential benefit of momentum-based dumbbell training for improving cognitive function in older adults with MCI.