Association Between Cardiovascular Disease Risk Factors and Mortality in Adults With Diabetes: A Stratified Analysis by Sex, Race, and Ethnicity.
Association Between Cardiovascular Disease Risk Factors and Mortality in Adults With Diabetes: A Stratified Analysis by Sex, Race, and Ethnicity.
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DOI：
10.3389/ijph.2022.1604472
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发表时间：
2022
影响因子：
4.6
通讯作者：
Egede, Leonard E.
中科院分区：
文献类型：
--
作者：
Savage, Kristina;Williams, Joni S.;Garacci, Emma;Egede, Leonard E.
目的：评估在具有全国代表性的糖尿病成人样本中，多种心血管疾病（CVD）风险因素与死亡率之间关系的性别和种族/民族差异。 研究方法：分析了2001-2010年国家健康和营养检查调查中3,503名糖尿病成人的数据及其截至2011年12月31日的相关死亡率数据。结局为死亡率;自变量为性别和人种/种族。协变量包括人口统计学、合并症和生活方式变量。考克斯比例风险回归用于检验死亡率和CVD危险因素之间的关系。 结果如下：在校正的分析中，舒张压和死亡率之间的相关性在性别和种族/民族之间存在显著差异（未校正p = 0.009;校正p = 0.042）。Kaplan-Meier生存曲线显示，与西班牙裔男性以及非西班牙裔黑人（NHB）和非西班牙裔白色（NHW）男性和女性相比，西班牙裔女性的生存率最高; NHW男性的生存概率最低。 结论：在这个具有全国代表性的样本中，分层分析显示，在每个种族/民族组中，女性的生存率高于男性，与所有其他组相比，西班牙裔女性的生存率最高。
Objectives: To assess sex and racial/ethnic differences in the relationship between multiple cardiovascular disease (CVD) risk factors and mortality among a nationally representative sample of adults with diabetes. Methods: Data were analyzed from 3,503 adults with diabetes from the National Health and Nutrition Examination Survey 2001–2010 and its linked mortality data through 31 December 2011. The outcome was mortality; the independent variables were sex and race/ethnicity. Covariates included demographics, comorbidity, and lifestyle variables. Cox proportional hazards regression was used to test associations between mortality and CVD risk factors. Results: In adjusted analyses, the association between diastolic blood pressure and mortality was significantly different by sex and race/ethnicity (unadjusted p = 0.009; adjusted p = 0.042). Kaplan-Meier survival curves showed Hispanic women had the highest survival compared to Hispanic men and Non-Hispanic Black (NHB) and Non-Hispanic White (NHW) men and women; NHW men had the lowest survival probability. Conclusion: In this nationally representative sample, stratified analyses showed women had higher survival rates compared to men within each race/ethnicity group, and Hispanic women had the highest survival compared to all other groups.
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DOI：
10.1111/dom.13039
发表时间：
2018-01
期刊：
Diabetes, obesity & metabolism
影响因子：
--
作者：
Tsujimoto T;Kajio H;Sugiyama T
通讯作者：
Sugiyama T
影响因子：
105.7
作者：
Huxley, R;Barzi, F;Woodward, M
通讯作者：
Woodward, M
影响因子：
158.5
作者：
Gaede, Peter;Lund-Andersen, Henrik;Pedersen, Oluf
通讯作者：
Pedersen, Oluf
影响因子：
120.7
作者：
Menke, Andy;Casagrande, Sarah;Cowie, Catherine C.
通讯作者：
Cowie, Catherine C.
影响因子：
16.2
作者：
Gregg EW;Cheng YJ;Saydah S;Cowie C;Garfield S;Geiss L;Barker L
通讯作者：
Barker L