Auditory evoked response to an oddball paradigm in children wearing cochlear implants
Auditory evoked response to an oddball paradigm in children wearing cochlear implants
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DOI：
10.1016/j.clinph.2023.02.179
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发表时间：
2023-03-23
影响因子：
4.7
通讯作者：
Gracco，Vincent L.
中科院分区：
文献类型：
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作者：
Deroche，Mickael L. D.;Wolfe，Jace;Gracco，Vincent L.
尽管植入人工耳蜗（CI）的儿童在其设备上取得了显着的成功，但个体结果仍存在相当大的差异。在这里，我们探讨是否听觉诱发电位记录在一个古怪的范式可以提供有用的标记，听觉处理在这儿科population.MethodsHigh-density脑电图（EEG）记录在75名儿童听标准和奇噪声刺激：25正常听力（NH）和50戴CI，分为高语言（HL）和低语言（LL）的能力。提取了三个指标：标准波形（N1-P2复合波）靠近顶点的第一负分量和第二正分量，差异波形Fz附近的失匹配负波（MMN）和Pz附近的晚期正分量（P3）。但是，许多具有年龄适当技能的CI儿童表现出与NH儿童相似的MMN和P3反应。此外，更大的和更早的P3（但不是MMN）与更好的识字skills.ConclusionsAuditory诱发反应区分儿童与CI的基础上，他们的好或差的技能与语言和literacy.SignificanceThis短的范例最终可以作为一个临床工具，用于跟踪植入儿童的发展成果。
ObjectiveAlthough children with cochlear implants (CI) achieve remarkable success with their device, considerable variability remains in individual outcomes. Here, we explored whether auditory evoked potentials recorded during an oddball paradigm could provide useful markers of auditory processing in this pediatric population.MethodsHigh-density electroencephalography (EEG) was recorded in 75 children listening to standard and odd noise stimuli: 25 had normal hearing (NH) and 50 wore a CI, divided between high language (HL) and low language (LL) abilities. Three metrics were extracted: the first negative and second positive components of the standard waveform (N1-P2 complex) close to the vertex, the mismatch negativity (MMN) around Fz and the late positive component (P3) around Pz of the difference waveform.ResultsWhile children with CIs generally exhibited a well-formed N1-P2 complex, those with language delays typically lacked reliable MMN and P3 components. But many children with CIs with age-appropriate skills showed MMN and P3 responses similar to those of NH children. Moreover, larger and earlier P3 (but not MMN) was linked to better literacy skills.ConclusionsAuditory evoked responses differentiated children with CIs based on their good or poor skills with language and literacy.SignificanceThis short paradigm could eventually serve as a clinical tool for tracking the developmental outcomes of implanted children.