Emerging viruses:: The case 'hantavirus'

Emerging viruses:: The case 'hantavirus'
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DOI:
10.1159/000067924
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发表时间:
2002-07-01
期刊:
影响因子:
4.6
通讯作者:
Krüger, DH
Krüger, DH
中科院分区:
医学4区
文献类型:
--
作者:
Ulrich, R;Hjelle, B;Krüger, DH

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本文简要总结了汉坦病毒感染的最新知识,并提出了汉坦病毒研究中需要进一步研究的问题。以下问题得到解决:(一)汉他病毒分布在世界各地,是什么导致新的爆发,(二)什么是已知的汉他病毒的演变,(三)如何可以汉他病毒的物种被定义,(四)什么是汉他病毒在人类的发病机制的决定因素,以及(五)什么问题与新疫苗和抗病毒治疗的发展。版权所有(C)2003 S. Karger AG,巴塞尔。
This review briefly summarises the recent knowledge about hantavirus infections and raises particular problems in hantavirus research that need further investigation. The following questions are addressed: (i) are hantaviruses distributed worldwide and what leads to new outbreaks, (ii) what is known about hantavirus evolution, (iii) how can hantavirus species be defined, (iv) what are the determinants of hantavirus pathogenesis in humans, and (v) what problems are associated with the development of new vaccines and antiviral therapeutics. Copyright (C) 2003 S. Karger AG, Basel.