Measurement of fatigue and discomfort in primary Sjogren's syndrome using a new questionnaire tool
Measurement of fatigue and discomfort in primary Sjogren's syndrome using a new questionnaire tool
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DOI：
10.1093/rheumatology/keh170
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发表时间：
2004-06-01
期刊：
影响因子：
5.5
通讯作者：
Platts, RG
中科院分区：
文献类型：
--
作者：
Bowman, SJ;Booth, DA;Platts, RG
Objective.疲劳是原发性干燥综合征（PSS）的一个突出症状。我们开始比较现有的仪器和一种新的工具来测量PSS的疲劳和全身不适，系统性红斑狼疮（SLE），类风湿性关节炎（RA）和健康对照。女性白人PSS患者组完成了一个新的问卷调查，从PSS患者自己的词汇，以及SF-36，WHOQOL-BREF和HAD量表。同时对SLE、RA患者和健康对照者进行问卷调查。在新工具中，每个疾病组在疲劳和全身不适的每个方面都与健康对照组有显着差异。躯体疲劳在类风湿关节炎中最严重，而精神疲劳在PSS和SLE中最严重。新工具中的躯体疲劳和不适方面与现有量表中的可比领域相关良好。PSS中的疲劳可以使用这种新的基于Sjogren's的心理测量仪器来测量。新的问卷工具比SF-36，WHOQOL-BREF和HAD在区分三种风湿性疾病与对照方面更敏感。
Objective. Fatigue is a prominent symptom in primary Sjogren's syndrome (PSS). We set out to compare existing instruments and a new tool for measuring fatigue and general discomfort in PSS, with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and healthy controls.Methods. Groups of female Caucasian PSS patients completed a new questionnaire developed from PSS patients' own vocabulary, as well as the SF-36, WHOQOL-BREF and HAD scales. For comparison, the questionnaire was also completed by groups of SLE and RA patients and healthy controls.Results. Each disease group differed significantly from healthy controls on each facet of fatigue and general discomfort in the new tool. Somatic fatigue was worst in RA, while mental fatigue was worst in PSS and SLE. The facets of somatic fatigue and discomfort in the new tool correlated well with comparable domains in existing scales.Conclusions. Fatigue in PSS can be measured using this new Sjogren's-based psychometric instrument. The new questionnaire tool was more sensitive than the SF-36, WHOQOL-BREF and HAD at distinguishing the three rheumatic disorders from controls.