Stromal cells of the mouse spleen.

Stromal cells of the mouse spleen.
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DOI:
10.3389/fimmu.2012.00201
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发表时间:
2012
影响因子:
7.3
通讯作者:
Kraal G
Kraal G
中科院分区:
医学2区
文献类型:
--
作者:
den Haan JM;Mebius RE;Kraal G

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脾白色髓中基质细胞的组成和功能在很大程度上类似于其他次级淋巴器官如淋巴结中的情况。基质细胞在脾的T和B细胞区中的淋巴细胞和髓样细胞的支持和引导中起重要作用。脾脏的主要差异在于细胞进入白色髓的方式和红髓中基质细胞的组成。本文从脾的功能出发,对白色髓和红髓间质细胞的特征进行了综述。
The composition and function of stromal cells in the white pulp of the spleen resemble to a large extent the situation in other secondary lymphoid organs such as lymph nodes. The stromal cells play an important role in the support and guidance of lymphocytes and myeloid cells in the T and B cell zones of the spleen. Major differences of the spleen are found in the way cells enter the white pulp and the composition of stromal cells in the red pulp. In this review, the features of stromal cells of both white and red pulp will be described in light of the function of the spleen.
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