Initial evaluation of a ceramic form as a reconstructive material for bone defects.
Initial evaluation of a ceramic form as a reconstructive material for bone defects.
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陶瓷形式作为骨缺损重建材料的初步评估。
DOI：
10.4012/dmj.19.381
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发表时间：
2000
影响因子：
2.5
通讯作者：
H. Yatani
中科院分区：
文献类型：
--
作者：
T. Kasai;K. Ishikawa;K. Suzuki;H. Yatani
将氧化铝形式和多孔磷灰石 apaceram 植入大鼠胫骨骨缺损中长达 12 周，并通过组织学研究组织反应，以初步评估这种陶瓷形式是否具有作为骨缺损重建材料的潜力。我们观察到，如果孔隙距表面的深度超过 1.0 毫米，即使在 12 周后，多孔磷灰石的孔隙内也没有骨形成。相比之下，我们早在植入后两周就观察到了氧化铝结构深处的骨组织。然而，尽管骨直接与多孔磷灰石接触，但在氧化铝模型周围形成的骨并不直接与氧化铝模型的框架接触。因此，我们得出结论，陶瓷形式作为骨缺损的重建材料具有潜在价值。如果可以用磷酸钙相关材料制备陶瓷模型，则该潜在价值将进一步增加。
Alumina form and a porous apatite, apaceram, were implanted in rat tibiae bone defects for up to 12 weeks and the tissue response was studied histologically as an initial evaluation of whether or not this ceramic form had potential as a reconstructive material for bone defects. We observed no bone formation inside the pores of porous apatite, even after 12 weeks, if the pores were deeper than 1.0 mm from the surface. In contrast, we observed bone tissue deep inside the alumina form as early as 2 weeks after implantation. However, the bone that formed around the alumina form did not directly contact with the frame of the alumina form, even though bone directly contacted with porous apatite. We concluded, therefore, that the ceramic form has potential value as a reconstructive material for bone defects. This potential value would be further increased if the ceramic form could be prepared with calcium phosphate-related materials.