Idiopathic orbital myositis.

Idiopathic orbital myositis.
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特发性眼眶肌炎。

DOI:
10.1097/00002281-199711000-00005
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发表时间:
1997
影响因子:
5.1
通讯作者:
Siatkowski Rm
Siatkowski Rm
中科院分区:
医学2区
文献类型:
--
作者:
I. Scott;Siatkowski Rm

文献摘要

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特发性眼眶肌炎是一种非特异性眼眶炎症亚型,主要累及眼外肌。它最常发生在年轻到中年的成年人中,女性占2比1。主要临床特征是眼球运动加剧的眼眶疼痛。其他常见的发现包括复视、眼球突出(通常是最小的)、结膜充血和球结膜水肿以及眶周水肿。甲状腺眼病常与眼眶肌炎相混淆,但后者的特点是起病更急,疼痛更剧烈,对全身皮质类固醇治疗反应迅速。超声和CT扫描显示肌腹增大,肌腱增厚,内部反射率低。虽然眼眶肌炎的原因是未知的,免疫介导的病理生理机制可能。本文综述了特发性眼眶肌炎的流行病学、诊断、病理生理学和治疗方面的最新研究结果。
Idiopathic orbital myositis is a subtype of nonspecific orbital inflammation primarily involving the extraocular muscles. It occurs most frequently in young to middle-aged adults with a 2 to 1 female predominance. The cardinal clinical feature is orbital pain exacerbated by eye movement. Other common findings include diplopia, proptosis (which is generally minimal), conjunctival injection and chemosis, and periorbital edema. Thyroid eye disease is commonly confused with orbital myositis, but the latter is characterized by a more acute onset, more severe pain, and a rapid response to systemic corticosteroid therapy. Echography and CT scanning reveal enlarged muscle bellies and thickened tendons, with low internal reflectivity echographically. Although the cause of orbital myositis is unknown, an immune-mediated pathophysiologic mechanism is likely. This review summarizes recent findings regarding the epidemiology, diagnosis, pathophysiology, and treatment of idiopathic orbital myositis.