Suprachiasmatic LH-releasing factor.
Suprachiasmatic LH-releasing factor.
复制标题
视交叉上 LH 释放因子。
DOI：
10.1159/000121888
复制
发表时间：
1969
影响因子：
4.1
通讯作者：
S. Mccann
中科院分区：
文献类型：
--
作者：
H. Schneider;D. Crighton;S. Mccann
正常发情雌性（E）和下丘脑损伤导致下丘脑持续发情（CE）大鼠的SME具有LRF活性，与单独用稀释剂孵育的成对对照半脑垂体相比，在SME存在下孵育的半脑垂体的LII释放显著增加（表1）。LF 1释放获得SME的大鼠病变似乎是小于与SME的从正常的女性。因此，在两个实验中直接比较了两种大鼠的SME活性。两种情况下，CE大鼠SME的LRF活性均低于正常动物（P< 0.01）。
SME’s from both normal females in estrus (E) and from rats showing hypothalamic constant estrus (CE) as a result of hypothalamic lesions possessed LRF activity, as indicated by a highly significant increase in LII release by pituitary halves incubated in the presence of SME in comparison with the paired control halves incubated with diluent alone (table 1). The LF1 release obtained from SME’s of rats with lesions appeared to be less than that obtained with SME’s from the normal females. Consequently, the activity of SME’s from the two types of rats was compared directly in two experiments. In both instances, the LRF activity from SME’s of CE rats was less than that of normal animals (P< 0.01).