Predictive ability of the total score of the Kihon checklist for the incidence of functional disability in older Japanese adults: An <scp>8‐year</scp> prospective study
Predictive ability of the total score of the Kihon checklist for the incidence of functional disability in older Japanese adults: An <scp>8‐year</scp> prospective study
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Kihon 检查表总分对日本老年人功能障碍发生率的预测能力：一项<scp>8 年</scp>前瞻性研究
DOI：
10.1111/ggi.14435
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发表时间：
2022
影响因子：
3.3
通讯作者：
Narazaki Kenji
中科院分区：
文献类型：
--
作者：
Matsuzaki Hideaki;Kishimoto Hiro;Nofuji Yu;Chen Tao;Narazaki Kenji
目的：通过8年的随访，探讨Kihon检查表总分（t - KCL评分）与功能障碍之间的关系，并探讨具有危险因素的基本模型中的t - KCL评分是否有助于增加老年人功能障碍的预测能力。方法对2209名年龄≥65岁、基线时无功能障碍的老年人进行随访。t - KCL评分采用基线调查问卷确定。功能性残疾的定义基于长期护理证明的信息。使用Cox比例风险模型检验t - KCL评分与功能障碍之间的关系。t - KCL评分对功能障碍的增量预测能力通过C -统计量、无类别净重分类改善（NRI）和综合判别改善（IDI）的差异来评估。结果中位随访期为7.8年，557名参与者出现功能障碍。t - KCL评分每增加1分，功能障碍的校正风险比（95%置信区间[CI]）为1.08（1.06-1.10）。在基本模型中加入t‐KCL评分显著提高了C‐统计量（95% CI），从0.747（0.728-0.768）提高到0.760（0.741-0.781）。当t‐KCL评分加入基本模型时，NRI和IDI分别为0.187 （95% CI: 0.095-0.287）和0.020 （95% CI: 0.012-0.027）。结论在8年的随访中，t - KCL评分与功能障碍有独立的正相关。此外，在基本模型中加入t - KCL评分可提高对功能障碍的预测能力。Geriatr Gerontol Int 2022；22日:723 - 729。
AimTo investigate the association between the total score of the Kihon checklist (t‐KCL score) and functional disability over an 8‐year follow‐up period, and to examine whether the t‐KCL score in the basic model with risk factors contributes to the incremental predictive ability for functional disability among older adults.MethodsWe followed 2209 older adults aged ≥65 years without functional disability at baseline. The t‐KCL score was determined using a baseline survey questionnaire. Functional disability was defined based on information from long‐term care certifications. The association between the t‐KCL score and functional disability was examined using the Cox proportional hazards model. The incremental predictive ability of the t‐KCL score for functional disability was evaluated by the difference of the C‐statistic, category‐free net reclassification improvement (NRI), and integrated discrimination improvement (IDI).ResultsThe median follow‐up period was 7.8 years, and 557 participants developed functional disability. The adjusted hazard ratio (95% confidence interval [CI]) of functional disability for a 1‐point increase of the t‐KCL score was 1.08 (1.06–1.10). Adding the t‐KCL score to the basic model significantly improved the C‐statistic (95% CI) from 0.747 (0.728–0.768) to 0.760 (0.741–0.781). When the t‐KCL score was added to the basic model, the NRI and IDI were 0.187 (95% CI: 0.095–0.287) and 0.020 (95% CI: 0.012–0.027), respectively.ConclusionsThe t‐KCL score had an independent positive association with functional disability over an 8‐year follow‐up. Furthermore, adding the t‐KCL score to the basic model improved the predictive ability for functional disability.Geriatr Gerontol Int 2022; 22: 723–729.