Dental Status and Compression of Life Expectancy with Disability
Dental Status and Compression of Life Expectancy with Disability
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DOI：
10.1177/0022034517713166
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发表时间：
2017-08-01
影响因子：
7.6
通讯作者：
Osaka, K.
中科院分区：
文献类型：
--
作者：
Matsuyama, Y.;Aida, J.;Osaka, K.
这项研究探讨了牙齿数量是否会降低发病率，以残疾预期寿命的缩短、健康预期寿命的延长和总体预期寿命来衡量。进行了一项前瞻性队列研究。 2010 年，日本对 126,438 名 65 岁以上社区居住老年人进行了自我报告基线调查，其中 85,161 人（67.4%）做出了回应。对功能障碍的发生和全因死亡率进行了 1,374 天的随访（随访率 = 96.1%）。应用性别分层疾病-死亡模型来估计 3 个健康转变（健康到死亡、健康到残疾、残疾到死亡）的调整后风险比 (HR)。还根据牙齿数量估计了预期寿命、健康预期寿命和残疾预期寿命的绝对差异。年龄、假牙使用情况、社会经济状况、健康状况和健康行为进行了调整。与无牙颌参与者相比，牙齿= 20颗的参与者从健康转变为死亡的风险较低（调整后的 HR，男性为 0.58 [95% CI，0.50-0.68]，女性为 0.70 [95% CI，0.57-0.85]）和从健康转变为残疾的风险较低（调整后的 HR，0.52 [95% CI，0.44-0.61]）男性为 0.58 [95% CI, 0.49-0.68] 为女性）。他们还更早地从残疾转变为死亡（调整后的 HR，男性为 1.26 [95% CI，0.99-1.60]，女性为 2.42 [95% CI，1.72-3.38]）。在年龄= 85岁的参与者中，与无牙颌参与者相比，拥有= 20颗牙齿的参与者的预期寿命较长（男性：+57天；女性：+15天）和健康预期寿命（男性：+92天；女性：+70天），而残疾预期寿命较短（男性：-35天；女性：-55天）。在年轻参与者和拥有 1 至 9 颗或 10 至 19 颗牙齿的参与者中也观察到了类似的关联。剩余牙齿的存在与发病率的显着压缩有关：在 1,374 天的随访中，日本老年人的残疾预期寿命被压缩了 35 至 55 天。
This study examined whether the number of teeth contributes to the compression of morbidity, measured as a shortening of life expectancy with disability, an extension of healthy life expectancy, and overall life expectancy. A prospective cohort study was conducted. A self-reported baseline survey was given to 126,438 community-dwelling older people aged >= 65 y in Japan in 2010, and 85,161 (67.4%) responded. The onset of functional disability and all-cause mortality were followed up for 1,374 d (follow-up rate = 96.1%). A sexstratified illness-death model was applied to estimate the adjusted hazard ratios (HRs) for 3 health transitions (healthy to dead, healthy to disabled, and disabled to dead). Absolute differences in life expectancy, healthy life expectancy, and life expectancy with disability according to the number of teeth were also estimated. Age, denture use, socioeconomic status, health status, and health behavior were adjusted. Compared with the edentulous participants, participants with = 20 teeth had lower risks of transitioning from healthy to dead (adjusted HR, 0.58 [95% confidence interval (CI), 0.50-0.68] for men and 0.70 [95% CI, 0.57-0.85] for women) and from healthy to disabled (adjusted HR, 0.52 [95% CI, 0.44-0.61] for men and 0.58 [95% CI, 0.49-0.68] for women). They also transitioned from disabled to dead earlier (adjusted HR, 1.26 [95% CI, 0.99-1.60] for men and 2.42 [95% CI, 1.72-3.38] for women). Among the participants aged = 85 y, those with = 20 teeth had a longer life expectancy (men: +57 d; women: +15 d) and healthy life expectancy (men: +92 d; women: +70 d) and a shorter life expectancy with disability (men: -35 d; women: -55 d) compared with the edentulous participants. Similar associations were observed among the younger participants and those with 1 to 9 or 10 to 19 teeth. The presence of remaining teeth was associated with a significant compression of morbidity: older Japanese adults' life expectancy with disability was compressed by 35 to 55 d within the follow-up of 1,374 d.