The genetics of response to volatile anesthetics in Caenorhabditis elegans.
The genetics of response to volatile anesthetics in Caenorhabditis elegans.
复制标题
秀丽隐杆线虫对挥发性麻醉剂反应的遗传学。
DOI：
10.1111/j.1749-6632.1991.tb33883.x
复制
发表时间：
1991
影响因子：
5.2
通讯作者：
Meneely,PM
中科院分区：
文献类型：
--
作者：
Morgan,PG;Sedensky,MM;Meneely,PM
RESULTSMutations in two genes, unc-79 and unc-80, confer altered responses to volatile anesthetics, in addition to an altered motor phenotype. When not in the presence of anesthetics, both these mutants are described as “fainters.” Their motion consists of short periods of normal motion, followed by an apparent refractory period lasting a few seconds during which their locomotion Unc-79 and unc-80 show increased sensitivity to the four anesthetics thiomethoxyflurane, methoxyflurane, chloroform, and halothane (group I, see TABLE 1 and FIG.
