Phase retardation measurement of retinal nerve fiber layer by polarization-sensitive spectral-domain optical coherence tomography and scanning laser polarimetry

Phase retardation measurement of retinal nerve fiber layer by polarization-sensitive spectral-domain optical coherence tomography and scanning laser polarimetry
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DOI:
10.1117/1.2841024
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发表时间:
2008-01-01
影响因子:
3.5
通讯作者:
Yasuno, Yoshiaki
Yasuno, Yoshiaki
中科院分区:
医学3区
文献类型:
--
作者:
Yamanari, Masahiro;Miura, Masahiro;Yasuno, Yoshiaki

文献摘要

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采用偏振敏感光谱域光学相干断层扫描(PS-SD-OCT)和激光偏振扫描(SLP)两种方法对活体人视网膜神经纤维层(RNFL)的相位延迟进行了定量测量。利用PS-SD-OCT测量的健康眼和青光眼眼的三维相位延迟体积计算出正面累积相位延迟图。结果表明,PS-SD-OCT和SLP测量的视乳头周围相位延迟曲线除视网膜血管附近外,具有相似的值。PS-SD-OCT可以测量RNFL的累积相位延迟以及SLP,这将允许对昏迷眼的RNFL进行评估。(C)2008年,由光学仪器工程师协会(Society of Photo-Optical Instrumentation Engineers)主办。
Phase retardation of in vivo human retinal nerve fiber layer (RNFL) is quantitatively measured by two methods-polarization-sensitive spectral-domain optical coherence tomography (PS-SD-OCT) and scanning laser polarimetry (SLP). An en face cumulative phase retardation map is calculated from the three-dimensional (3-D) phase retardation volume of healthy and glaucomatous eyes measured by PS-SD-OCT. It is shown that the phase retardation curves around the optic nerve head measured by PS-SD-OCT and SLP have similar values except near the retinal blood vessels. PS-SD-OCT can measure the cumulative phase retardation of RNFL as well as SLP, which will allow the evaluation of RNFL for glaucomatous eyes. (C) 2008 Society of Photo-Optical Instrumentation Engineers.