Incidence and predictors of left ventricular function change following ST-segment elevation myocardial infarction.

Incidence and predictors of left ventricular function change following ST-segment elevation myocardial infarction.
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ST段抬高心肌梗塞后左心室功能变化的发生率和预测因子。

DOI:
10.3389/fcvm.2023.1079647
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发表时间:
2023
影响因子:
3.6
通讯作者:
Chen H
Chen H
中科院分区:
医学3区
文献类型:
--
作者:
Liu C;Guo M;Cui Y;Wu M;Chen H

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本研究的目的是评估ST段抬高型心肌梗死(STEMI)患者接受直接经皮冠状动脉介入治疗(PCI)后左心功能改变的发生率和预测因素。本研究纳入2015年1月至2016年12月间接受直接经皮冠状动脉介入治疗的312例STEMI患者。采用多元Logistic回归分析评价长期随访后左室射血分数(LVEF)改善的独立预测因素。最后分析186例患者从基线到随访期间的LVEF变化。平均年龄61.3 ± 12.5岁,其中男性占78.5%。STEMI后随访时间的中位数为1021(389-1,947)天。通过长期随访,54.3%的患者术后左心室射血分数下降,45.7%的患者术后左心功能改善。Logistic回归分析显示,较低的峰值肌钙蛋白I、非前壁STEMI、较低的基线LVEF和既往无心肌梗死病史与LVEF改善独立相关。接受直接经皮冠状动脉介入治疗的STEMI患者中有54.3%的患者在远期随访期左心室射血分数下降。根据基线特征可以预测LVEF恢复情况。
The purpose of the study was to assess the incidence and predictors of left ventricular function change in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary PCI. 312 patients with STEMI who received primary percutaneous coronary intervention (PCI) between January 2015 and December 2016 were consecutively enrolled in this study. Multiple logistic regression analysis was used to evaluate independent predictors of left ventricular ejection fraction (LVEF) improvement after long-term follow-up. We finally analyzed the LVEF change in 186 patients from baseline to follow-up. The mean age was 61.3 ± 12.5 years, with 78.5% being male. The median duration of follow-up after STEMI was 1,021 (389–1,947) days. 54.3% had a decrease in LVEF and 45.7% experienced an improvement in LV function after primary PCI through long-term follow-up. Logistic regression analysis showed lower peak troponin I, non-anterior STEMI, lower baseline LVEF, and no previous myocardial infarction history were independently associated with LVEF improvement. 54.3% of patients with STEMI undergoing primary PCI had a decrease in LVEF during long-term follow-up. LVEF recovery can be predicted by baseline characteristics.
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