On the role of oxygen in fabricating microfluidic channels with ultraviolet curable materials
On the role of oxygen in fabricating microfluidic channels with ultraviolet curable materials
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DOI：
10.1039/b810348h
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发表时间：
2008-01-01
期刊：
影响因子：
6.1
通讯作者：
Suh, Kahp Y.
中科院分区：
文献类型：
--
作者：
Jeong, Hoon Eui;Suh, Kahp Y.
我们提出了氧气的影响上的不可逆键合的微通道，使用紫外线（UV）固化材料的聚氨酯丙烯酸酯（普阿）。通过将具有微流体通道的印模的顶层和由玻璃或聚对苯二甲酸乙二醇酯（PET）膜基底上的普阿涂层组成的底层结合来制造微通道。所得通道是普阿材料的均匀导管。为了找到最佳的粘合条件，底层在不同的氧气浓度和UV暴露时间下在恒定的UV强度（10 mW cm（-2））下固化。我们的实验和理论研究表明，通道键合的严重影响的浓度的氧气无论是在捕获的空气或渗透的空气的通道。此外，需要最佳的UV暴露时间以防止通道堵塞或不粘合。
We present the effects of oxygen on the irreversible bonding of a microchannel using an ultraviolet (UV) curable material of polyurethane acrylate (PUA). Microchannels were fabricated by bonding a top layer with impressions of a microfluidic channel and a bottom layer consisting of a PUA coating on a glass or a polyethylene terephthalate (PET) film substrate. The resulting channel is a homogeneous conduit of the PUA material. To find optimal bonding conditions, the bottom layer was cured under different oxygen concentration and UV exposure time at a constant UV intensity (10 mW cm(-2)). Our experimental and theoretical studies revealed that the channel bonding is severely affected by the concentration of oxygen either in the form of trapped air or permeated air out of the channel. In addition, an optimal UV exposure time is needed to prevent clogging or non-bonding of the channel.