The distribution of respiration-related and swallowing-related motoneurons innervating the rat genioglossus muscle
The distribution of respiration-related and swallowing-related motoneurons innervating the rat genioglossus muscle
复制标题
支配大鼠颏舌肌的呼吸相关和吞咽相关运动神经元的分布
DOI：
10.1080/08990220120113020
复制
发表时间：
2002
影响因子：
0.9
通讯作者：
K. Furusawa
中科院分区：
文献类型：
--
作者：
K. Yasuda;Yoko Nakayama;Mizuho Tanaka;Mikiko Tanaka;Ryota Mori;K. Furusawa
本研究试图确定颏舌神经呼吸和吞咽运动神经元胞体的位置内的舌下神经（XII）核使用电生理和形态学研究。颏舌肌由第十二内侧神经的颏舌分支支配。颏舌肌分支在肌的入口处向下颌骨和舌的方向分开。5只大鼠中有5只在朝向下颌骨的内侧XII分支中表现出吞咽相关和吞咽相关的爆发。所有5只大鼠在朝向舌头的内侧XII分支中也显示吞咽相关爆发。此外，辣根过氧化物酶结合小麦胚芽凝集素（HRP：WGA）被注入到近端切割结束的每个分支。当HRP：WGA注射到下颌骨方向的分支中时，在XII核的腹内侧亚核的外侧区域中检测到HRP标记的细胞，从0.7至1.2 mm延伸到喙。另一方面，注射到下颌骨方向的分支后，在第十二核的腹内侧亚核中检测到HRP标记细胞，从0.3至1.2 mm延伸到喙。这些结果提供了证据，颏舌呼吸相关和吞咽相关的运动神经元位于不同的部分内的腹内侧亚核的第十二核。
The present study was an attempt to identify the location of genioglossal respiratory and swallowing motoneuron cell bodies within the hypoglossal (XII) nucleus using both electrophysiological and morphological studies. The genioglossus muscle is innervated by the genioglossal branch of the medial XII nerve. At the entrance to the muscle, the genioglossal branch divides in the directions of the mandible and tongue. Five of five rats displayed both respiratory-related and swallowing-related bursts in the medial XII branch towards the mandible. All five rats also displayed swallowing-related bursts in the medial XII branch towards the tongue. In addition, horseradish peroxidase conjugated to wheatgerm agglutinin (HRP:WGA) was injected into the proximal cut ends of each branch. When HRP:WGA was injected into the branch in the direction of the mandible, HRP-labeled cells were detected in the lateral region of the ventromedial subnucleus in the XII nucleus, extending from 0.7 to 1.2 mm rostral to the obex. On the other hand, after injection into the branch in the direction of the mandible, HRP-labeled cells were detected in the ventromedial subnucleus of the XII nucleus, extending from 0.3 to 1.2 mm rostral to the obex. These results provide evidence that genioglossal respiration-related and swallowing-related motoneurons are located in different portions within the ventromedial subnucleus of the XII nucleus.