Solid state ultraviolet laser (213 nm) ablation of the cornea and synthetic collagen lenticules
Solid state ultraviolet laser (213 nm) ablation of the cornea and synthetic collagen lenticules
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固态紫外激光（213 nm）消融角膜和合成胶原微透镜
DOI：
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发表时间：
1991
影响因子：
2.4
通讯作者：
G. Waring
中科院分区：
文献类型：
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作者：
R. Gailitis;Q. Ren;K. Thompson;Jui;G. Waring
我们使用带有非线性光学晶体的 Q 开关 Nd:YAG 激光器来产生第五 (213 nm) 和第四 (266 nm) 谐波频率。使用这两个波长，我们消融了新鲜的猪角膜和 I 型胶原合成表皮角膜成形术微透镜。对于 213 nm 消融，辐射暴露为 1.3 J/cm2。表层角膜移植微透镜的消融率为每脉冲 0.23 μm。我们用光学显微镜、透射电子显微镜和扫描电子显微镜检查了所有组织。 213 nm 消融的组织学显示干净的消融坑，胶原片层破坏最小，损伤区域小于 1μm。相比之下，266 nm 辐射在边缘显示出更多的炭化，损伤区深度约为 25 μm，基质层被破坏。
We used a Q‐switched Nd:YAG laser with non‐linear optical crystals to produce the 5th (213 nm) and the 4th (266 nm) harmonic frequencies. Using these two wavelengths, we ablated fresh porcine corneas and type I collagen synthetic epikeratoplasty lenticules. For the 213‐nm ablation, radiant exposure was 1.3 J/cm2. The ablation rate was 0.23 μm per pulse for the epikeratoplasty lenticules. We examined all tissues with light microscopy, transmission electron microscopy, and scanning electron microscopy. Histology for the 213‐nm ablation showed a clean ablation crater with minimal collagen lamellae disruption and a damage zone less than 1μm. In comparison, the 266 nm radiation showed more charring at the edges with a damage zone approximately 25 μm deep with disruption of the stromal lamella.
近视准分子激光屈光角膜切除术：临床相关性分析。
DOI：
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发表时间：
1990
期刊：
Refractive & corneal surgery
影响因子：
--
作者：
Liu,JC;McDonald,MB;Varnell,R;Andrade,HA
通讯作者：
Andrade,HA