THE AMERICAN-RHEUMATISM-ASSOCIATION 1987 REVISED CRITERIA FOR THE CLASSIFICATION OF RHEUMATOID-ARTHRITIS

THE AMERICAN-RHEUMATISM-ASSOCIATION 1987 REVISED CRITERIA FOR THE CLASSIFICATION OF RHEUMATOID-ARTHRITIS
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DOI:
10.1002/art.1780310302
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发表时间:
1988-03-01
影响因子:
--
通讯作者:
HUNDER, GG
HUNDER, GG
中科院分区:
其他
文献类型:
--
作者:
ARNETT, FC;EDWORTHY, SM;HUNDER, GG

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类风湿性关节炎 (RA) 分类的修订标准是根据对 262 名当代连续研究的 RA 患者和 262 名患有 RA 以外的风湿性疾病(非 RA)的对照受试者的计算机分析制定的。新标准如下:1)关节内及其周围的晨僵持续至少1小时才能得到最大程度的改善; 2) 医生观察到3个或更多关节区域的软组织肿胀(关节炎); 3)近端指间关节、掌指关节或腕关节肿胀(关节炎); 4)对称性肿胀(关节炎); 5)类风湿结节; 6) 类风湿因子的存在; 7) 手和/或腕关节的放射线侵蚀和/或关节周围骨质减少。标准 1 至 4 必须已存在至少 6 周。类风湿性关节炎的定义是存在 4 个或更多标准,不需要进一步的资格(典型的、明确的或可能的)或排除列表。此外,还提供了一个“分类树”模式,其性能与传统(7 中的 4)格式相同。与非 RA 风湿病对照受试者相比,新标准对 RA 的敏感性为 91-94%,特异性为 89%。
The revised criteria for the classification of rheumatoid arthritis (RA) were formulated from a computerized analysis of 262 contemporary, consecutively studied patients with RA and 262 control subjects with rheumatic diseases other than RA (non-RA). The new criteria are as follows: 1) morning stiffness in and around joints lasting at least 1 hour before maximal improvement; 2) soft tissue swelling (arthritis) of 3 or more joint areas observed by a physician; 3) swelling (arthritis) of the proximal interphalangeal, metacarpophalangeal, or wrist joints; 4) symmetric swelling (arthritis); 5) rheumatoid nodules; 6) the presence of rheumatoid factor; and 7) radiographic erosions and/or periarticular osteopenia in hand and/or wrist joints. Criteria 1 through 4 must have been present for at least 6 weeks. Rheumatoid arthritis is defined by the presence of 4 or more criteria, and no further qualifications (classic, definite, or probable) or list of exclusions are required. In addition, a "classification tree" schema is presented which performs equally as well as the traditional (4 of 7) format. The new criteria demonstrated 91-94% sensitivity and 89% specificity for RA when compared with non-RA rheumatic disease control subjects.