CASE REPORT: Crohn's Disease with Parkinsonism Due to Long-Term Total Parenteral Nutrition
CASE REPORT: Crohn's Disease with Parkinsonism Due to Long-Term Total Parenteral Nutrition
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病例报告：长期全肠外营养导致克罗恩病伴帕金森病
DOI：
10.1023/a:1023072217843
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发表时间：
2003
影响因子：
3.1
通讯作者：
T. Arakawa
中科院分区：
文献类型：
--
作者：
N. Kamata;N. Oshitani;R. Oiso;T. Kawachiya;M. Inagawa;D. Kawashima;M. Iimuro;M. Sogawa;Y. Jinno;K. Watanabe;S. Nakamura;K. Higuchi;T. Matsumoto;T. Arakawa
帕金森综合征分为两组：特发性和继发性，如药物引起或中毒(CO、Mn)、动脉硬化、慢性硬膜下血肿、感染和变性。主要症状是四肢震颤、书写困难、步态障碍和面具样。长期TPN期间的锰中毒及其相关的中枢神经系统异常已有报道(2-4)。
DISCUSSIONParkinson syndrome is classified into two groups: idiopathic and secondary, such as drug-induced, or due to intoxication (CO, Mn), arteriosclerosis, chronic subdural hematoma, infection, and degeneration. The main symptoms are tremons of the extremities, dysgraphia, gait disturbance and masklike face. Mn toxicity during long-term TPN and its associated CNS abnormalities have previously been reported (2–4).