Corrosion and biocompatibility behaviour of zirconia coating by EBPVD for biomedical applications
Corrosion and biocompatibility behaviour of zirconia coating by EBPVD for biomedical applications
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DOI：
10.1016/j.surfcoat.2017.11.047
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发表时间：
2018-01-25
影响因子：
5.4
通讯作者：
Muthaiah, Bavanilatha
中科院分区：
文献类型：
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作者：
Kaliaraj, Gobi Saravanan;Vishwakarma, Vinita;Muthaiah, Bavanilatha
采用电子束物理气相沉积（EBPVD）技术在316 L不锈钢基体上沉积了氧化锆（ZrO2）薄膜。利用X射线衍射仪（XRD）、原子力显微镜（AFM）和扫描电子显微镜（SEM）研究了ZrO2薄膜的微观结构。亲水性观察到的氧化锆涂层膜和最少的亲水性行为被发现在裸露的316 L SS基板。细菌粘附试验针对变形链球菌（S.结果表明，ZrO_2薄膜对细菌在其表面的粘附具有保护作用。在体外细胞毒性和生物相容性的氧化锆薄膜的行为进行了研究，使用成纤维细胞系，表现出高度的细胞活力和增殖率，而不是裸露的316 L SS基板。在含0.2%和2%氟化钠（NaF）的酸化人工唾液（AS）溶液中进行电化学研究。结果表明，ZrO2涂层316 L SS显示出优异的耐腐蚀性能，可以被认为是一种潜在的牙科生物植入物。
In the present study, zirconia (ZrO2) film was deposited onto 316L SS substrate by electron beam physical vapour deposition (EBPVD) technique. The microstructure of the ZrO2 film was studied using X-ray diffraction (XRD) and atomic force microscopy (AFM) and scanning electron microscopy (SEM). Hydrophilic nature was observed on ZrO2 coated film and least hydrophilic behaviour was found on bare 316L SS substrate. The bacterial adhesion test was performed against Streptococcus mutans (S. mutans) and revealed that ZrO2 film protects the bacterial adhesion on its surface. In-vitro cytotoxicity and biocompatibility behaviour of ZrO2 film were investigated using fibroblast cell line, which exhibited high degree of cell viability and proliferation rate rather than bare 316L SS substrate. Electrochemical studies were performed in acidulated artificial saliva (AS) solution containing 0.2% and 2% of sodium fluoride (NaF). The results revealed that ZrO2 coated 316L SS showed excellent corrosion resistant behaviour and can be considered as a potential bioimplant for dental applications.