ENZYMATIC FORMATION OF PSYCHOTOMIMETIC METABOLITES FROM NORMALLY OCCURRING COMPOUNDS
ENZYMATIC FORMATION OF PSYCHOTOMIMETIC METABOLITES FROM NORMALLY OCCURRING COMPOUNDS
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DOI：
10.1126/science.134.3475.343
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发表时间：
1961-01-01
期刊：
影响因子：
56.9
通讯作者：
AXELROD, J
中科院分区：
文献类型：
--
作者：
AXELROD, J
一种酶已被发现N-甲基化血清素和色胺为拟精神代谢产物，丁氟丁宁和N，N-二甲基色胺。该酶高度定位于兔肺，也能n -甲基化苯乙胺衍生物，如酪胺、苯乙胺、美斯卡灵和多巴胺。
An enzyme has been found that N-methylates serotonin and tryptamine to psychotomimetic metabolites, bufotenine and N,N-dimethyltryptamine. This enzyme is highly localized in the rabbit lung and also N-methylates phenylethylamine derivatives such as tyramine, phenylethylamine, mescaline, and dopamine.