Chiral Hypervalent Iodine(III) Catalyst Promotes Highly Enantioselective Sulfonyl- and Phosphoryl-oxylactonizations
Chiral Hypervalent Iodine(III) Catalyst Promotes Highly Enantioselective Sulfonyl- and Phosphoryl-oxylactonizations
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DOI：
10.1021/acs.orglett.6b03631
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发表时间：
2017-01-06
期刊：
影响因子：
5.2
通讯作者：
Masson, Geraldine
中科院分区：
文献类型：
--
作者：
Gelis, Coralie;Dumoulin, Audrey;Masson, Geraldine
使用化学计量或催化量的手性芳基-λ（3）-碘烷实现了4-戊烯酸的高效的对映选择性高价碘促进的双内酰化反应：该反应提供了直接获得宽范围的磺酰氧基-和磷酰氧基-γ-丁内酯的途径，具有可观的产率和中等至优异的对映选择性。
An efficient enantioselective hypervalent iodine promoted oxylactonization of 4-pentenoic acids has been achieved using stoichioimetric or a catalytic amount of chiral aryl-lambda(3)-iodane: This reaction provides straightforward access to a wide range of sulfonyloxy- and phosphoryloxy-gamma-butyrolactones in respectable yields with moderate to excellent enantioselectivities.