Expanded criteria for liver transplantation in patients with hepatocellular carcinoma: A report from the International Registry of Hepatic Tumors in Liver Transplantation

Expanded criteria for liver transplantation in patients with hepatocellular carcinoma: A report from the International Registry of Hepatic Tumors in Liver Transplantation
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DOI:
10.1002/lt.21095
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发表时间:
2007-03-01
影响因子:
4.6
通讯作者:
Klintmalm, Goeran B.
Klintmalm, Goeran B.
中科院分区:
医学2区
文献类型:
--
作者:
Onaca, Nicholas;Davis, Gary L.;Klintmalm, Goeran B.

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肝细胞癌(HCC)是肝移植(LT)的常见适应症。目前,器官共享联合网络(United Network for Organ Sharing)批准,对于符合米兰标准的HCC患者,即影像学检查确定的单个肿瘤≥5cm或≥3个肿瘤≥3cm。我们分析了来自1206例肝细胞癌患者的国际肝脏肿瘤登记处的数据。经大体病理检查确定肿瘤大小及数目。单一肿瘤患者的Kaplan-Meier无复发生存率
Hepatocellular carcinoma (HCC) is a common indication for liver transplantation (LT). Currently, deceased donor LT is approved by the United Network for Organ Sharing for patients with HCC who meet the Milan criteria of a single tumor up to 5 cm or up to 3 tumors up to 3 cm as determined by imaging studies. We analyzed data in the International Registry of Hepatic Tumor:3 in Liver Transplantation from 1,206 patients with HCC. Tumor size and number were determined by gross pathologic,examination. Kaplan-Meier recurrence-free survival in patients with a single tumor