Complete nucleotide sequence of the E. coli glyA gene.
Complete nucleotide sequence of the E. coli glyA gene.
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大肠杆菌 glyA 基因的完整核苷酸序列。
DOI：
10.1093/nar/11.7.2065
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发表时间：
1983
影响因子：
14.9
通讯作者：
Stauffer,GV
中科院分区：
文献类型：
--
作者：
Plamann,MD;Stauffer,LT;Urbanowski,ML;Stauffer,GV
已经确定了escherichiacoliglyagene的核苷酸序列。由DNA序列预测的氨基酸序列由417个残基组成。在编码区之后，在glyagene的转录终止区之前有185个核苷酸序列。该区域之前是富含G - C的序列，一旦转录，可以形成稳定的茎环结构，然后是富含a - t的序列，其中转录似乎终止。在翻译终止位点和转录终止区之间有一长串对称区域和许多较小的对称区域。这些茎环结构与其他原核操纵子的顺反子间元件具有显著的同源性，可能在调节glyagene的表达中起作用。
The nucleotide sequence of theEscherichiacoliglyAgene has been determined. The amino acid sequence predicted from the DNA sequence consists of 417 residues. After the coding region there is a 185 nucleotide sequence preceding the proposed transcription termination region for theglyAgene. This region is preceded by a G‐C rich sequence that could form a stable stem–loop structure once transcribed, followed by an A–T rich sequence within which transcription appears to terminate. There is a long region of dyad symmetry and numerous smaller symmetrical regions between the site of translation termination and the proposed transcription termination region. These stem–loop structures show remarkable homology with intercistronic elements of other prokaryotic operons and may play a role in the regulation ofglyAgene expression.