Peers, play, and performance to build social salience in autistic youth: A multisite randomized clinical trial.
Peers, play, and performance to build social salience in autistic youth: A multisite randomized clinical trial.
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DOI：
10.1037/ccp0000821
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发表时间：
2023-05
影响因子：
5.9
通讯作者：
B. Corbett;S. White;M. Lerner;Kristopher J Preacher;Marko Klemenčić;G. L. Simmons;Jennifer Pilkington
中科院分区：
文献类型：
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作者：
B. Corbett;S. White;M. Lerner;Kristopher J Preacher;Marko Klemenčić;G. L. Simmons;Jennifer Pilkington
目的自闭症谱系障碍（ASD）患者的社会能力和社会显著性显著降低。SENSE Theatre是一种以同伴为中介的基于剧院的干预方法，已证明治疗后在面部记忆和社会沟通方面有所收获。多中心随机临床试验在测试前、测试后和随访时比较了实验（EXP; SENSE Theatre）与主动控制条件（ACC; Tackling Teenage Training，TTT）。假设EXP组将表现出比ACC组更大的偶然面部记忆（IFM）和更好的社会行为（与新同伴的互动）和社会功能（日常生活中的社会参与），并且测试后IFM将介导对后续社会行为和功能的治疗效果。方法290名参与者随机分为EXP组（N = 144）和ACC组（N = 146）。符合方案样本（≥ 7/10次）纳入207名10-16岁自闭症儿童。事件相关电位测量IFM。天真的测试者测量社会行为（声音表达力，和谐质量，社交焦虑）和功能（社会沟通）。使用结构方程模型评估治疗效果。结果SENSE Theatre参与者在后测时表现出显著更好的IFM（B = .874，p = .039），并通过后测IFM对后续声乐表现力a × B = .064，90%CI [.014，.118]和融洽质量a × B = .032，90%CI [.002，.087]产生显著的间接影响。结论：感觉剧场提高了IFM所反映的社会显著性，这反过来又影响了声音的表现力和融洽的质量。结果表明，支持社会认知和社会显着性驱动的神经机制参与治疗，并具有广泛的，间接的临床意义的功能结果相关的自闭症的核心症状。（PsycInfo数据库记录（c）2023阿帕，保留所有权利）。
OBJECTIVE Individuals with autism spectrum disorder (ASD) have significant impairment in social competence and reduced social salience. SENSE Theatre, a peer-mediated, theater-based intervention has demonstrated posttreatment gains in face memory and social communication. The multisite randomized clinical trial compared the Experimental (EXP; SENSE Theatre) to an Active Control Condition (ACC; Tackling Teenage Training, TTT) at pretest, posttest, and follow-up. It was hypothesized that the EXP group would demonstrate greater incidental face memory (IFM) and better social behavior (interaction with novel peers) and social functioning (social engagement in daily life) than the ACC group, and posttest IFM would mediate the treatment effect on follow-up social behavior and functioning. METHOD Two hundred ninety participants were randomized to EXP (N = 144) or ACC (N = 146). Per protocol sample (≥ 7/10 sessions) resulted in 207 autistic children 10-16 years. Event-related potentials measured IFM. Naive examiners measured social behavior (Vocal Expressiveness, Quality of Rapport, Social Anxiety) and functioning (Social Communication). Structural equation modeling was used to assess treatment effects. RESULTS SENSE Theatre participants showed significantly better IFM (b = .874, p = .039) at posttest, and significant indirect effects on follow-up Vocal Expressiveness a × b = .064, with 90% CI [.014, .118] and Quality of Rapport a × b = .032, with 90% CI [.002, .087] through posttest IFM. CONCLUSIONS SENSE Theatre increases social salience as reflected by IFM, which in turn affected Vocal Expressiveness and Quality of Rapport. Results indicate that a neural mechanism supporting social cognition and driven by social salience is engaged by the treatment and has a generalized, indirect effect on clinically meaningful functional outcomes related to core symptoms of autism. (PsycInfo Database Record (c) 2023 APA, all rights reserved).