FUNCTIONAL-MORPHOLOGY OF TESTIS

FUNCTIONAL-MORPHOLOGY OF TESTIS
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DOI:
10.1095/biolreprod18.1.1
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发表时间:
1978-01-01
影响因子:
3.6
通讯作者:
CAVICCHIA, JC
CAVICCHIA, JC
中科院分区:
生物学2区
文献类型:
--
作者:
DYM, M;CAVICCHIA, JC

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在过去的十年中,许多研究者的注意力已经被导向支持细胞在精子发生过程中的作用。支持细胞具有一系列令人印象深刻的功能(福塞特,1975; Dym,1977 a)。其中包括:1)分泌液体进入小管腔; 2)合成蛋白质; 3)吞噬退化的生殖细胞和残留体; 4)在精子释放现象中发挥作用; 5)在生殖细胞从基部到管腔的运动中发挥作用; 6)类固醇的代谢; 7)血-睾丸屏障的形成。其他数据表明,支持细胞是FSH在睾丸中的主要作用部位。由于对支持细胞的大量研究活动,很少关注生殖细胞分化。在本文中,我将回顾最近的观察猴生殖细胞的精细结构,并提出一些新的数据,血睾丸屏障。此外,生精上皮的初步形态计量学研究将提交。
During the past decade the attention of many investigators has been directed to the role of the Sertoli cell in the spermatogenic process. An impressive array of functions has been assigned to Sertoli cells (Fawcett, 1975; Dym, 1977a). These include: 1) secretion of fluid into the tubule lumen; 2) synthesis of proteins; 3) phagocytosis of degenerating germ cells and residual bodies; 4) a role in the sperm release phenomenon; 5) a role in the movement of germ cells from base to lumen; 6) metabolism of steroids; 7) the formation of the blood-testis barrier. Other data demonstrate that the Sertoli cell is the principal site of action for FSH in the testis. As a result of this abundant research activity on Sertoli cells, less attention has been devoted to germ cell differentiation. In this paper I will review recent observations on the fine structure of monkey germ cells and present some new data on the blood-testis barrier. In addition, a preliminary morphometric study of the seminiferous epithelium will be presented.