Unified dosimetry index (UDI): a figure of merit for ranking treatment plans

Unified dosimetry index (UDI): a figure of merit for ranking treatment plans
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DOI:
10.1120/jacmp.v9i3.2803
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发表时间:
2008-01-01
影响因子:
2.1
通讯作者:
Meek, Allen
Meek, Allen
中科院分区:
医学4区
文献类型:
--
作者:
Akpati, Hilary;Kim, ChangSeon;Meek, Allen

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我们制定了一个统一的剂量测定指数(UDI),计算任何给定的治疗计划,其剂量覆盖,一致性,均匀性和剂量梯度方面的偏差相对维斯一个理想的计划(我们定义为完美的剂量覆盖,一致性,均匀性,并逐步下降到零剂量计划靶体积外的剂量测定计划)。为了验证UDI评分系统,回顾性评价了21例立体定向颅骨放射外科病例。在BrainSCAN治疗计划系统(BrainLAB,Feldkirchen,德国)上使用6至8个非共面静态射束(经微型多叶准直器(mMLC)准直)对病例进行计划。我们建议一种技术,用于创建一个排名系统,可用于计划评估和多个计划之间的比较。根据这一制度,治疗计划分为“优秀”、“良好”、“一般”或“较差”。建议的排名系统可以用来作为一个一般性的指导,产生一个最佳的外射束放射治疗的剂量计划。
We have formulated a unified dosimetry index (UDI) that computes, for any given treatment plan, its deviations in terms of dose coverage, conformity, homogeneity, and dose gradient vis-a-vis an ideal plan ( which we define as a dosimetry plan of perfect dose coverage, conformity, homogeneity, and step-wise fall-off to zero dose outside the planning target volume). In order to validate the UDI scoring system, 21 stereotactic cranial radiosurgery cases were evaluated retrospectively. The cases were planned on the BrainSCAN treatment planning system (BrainLAB, Feldkirchen, Germany) using 6 to 8 non-coplanar static beams collimated with the micro multi-leaf collimator (mMLC). We suggest a technique for creating a ranking system that can be utilized for plan evaluation and comparison between multiple plans. Under this system treatment plans are classified as "excellent", "good", "average", or "poor". The proposed ranking system can be utilized as a general guide for generating an optimal dosimetry plan for external beam radiation therapy.