Concordance and characterization of massively parallel sequencing at 58 STRs in a Tibetan population.
Concordance and characterization of massively parallel sequencing at 58 STRs in a Tibetan population.
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西藏人群 58 个 STR 大规模并行测序的一致性和表征
DOI：
10.1002/mgg3.1626
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发表时间：
2021-04
影响因子：
2
通讯作者：
Xie J
中科院分区：
文献类型：
--
作者：
Li H;Zhang C;Song G;Ma K;Cao Y;Zhao X;Yang Q;Xie J
大规模平行测序（MPS）是一种很有前途的补充方法，法医案例工作中的短串联重复序列（STR）基因分型，由于与传统的毛细管电泳（CE）相比，一些有利的功能。然而，MPS在个案工作中的应用需要来自全球人群的可访问数据集，以丰富基于序列的STR基因型的等位基因频率。
Massively parallel sequencing (MPS) is a promising supplementary method for forensic casework in short tandem repeats (STRs) genotyping, owing to several advantageous features in comparison to traditional capillary electrophoresis (CE). However, the application of MPS in casework requires accessible datasets from the worldwide population to enrich the allele frequencies of sequence‐based STR genotypes.