AIRWAY MACROPHAGES - THE IMPORTANCE OF THE FIXATION METHOD
AIRWAY MACROPHAGES - THE IMPORTANCE OF THE FIXATION METHOD
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DOI：
10.1164/arrd.1984.129.5.823
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发表时间：
1984-01-01
期刊：
影响因子：
--
通讯作者：
KAVET, RI
中科院分区：
文献类型：
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作者：
BRAIN, JD;GEHR, P;KAVET, RI
比较两种固定方法（血管内灌注和气管内灌注）对[仓鼠]气道和肺泡巨噬细胞数量、分布和形态的影响。注射固定剂后，气道巨噬细胞数量减少，仅为血管内灌注后的32.6%。巨噬细胞在气道中可能具有重要的生理和病理作用。固定的方法对于保存它们的数量和位置至关重要。
Two methods of fixation, intravascular perfusion and intratracheal instillation, were compared with regard to the number, distribution and appearance of [hamster] airway and alveolar macrophages. With instillation of fixative, the number of airway macrophages present was reduced to only 32.6% of that seen after intravascular perfusion. Macrophages may have important physiologic and pathologic roles in the airways. The method of fixation is crucial for preservation of their numbers and location.