Altered nuclear transfer in stem-cell research - a flawed proposal.
Altered nuclear transfer in stem-cell research - a flawed proposal.
复制标题
干细胞研究中改变核移植——一个有缺陷的提议。
DOI：
10.1056/nejmp048348
复制
发表时间：
2004
期刊：
影响因子：
--
通讯作者：
C. Jennings
中科院分区：
文献类型：
--
作者：
D. Melton;G. Daley;C. Jennings
人类胚胎干细胞的研究是一个引起公众激烈争论的问题，主要是因为这种细胞的衍生需要破坏人类囊胚，一些人认为这一过程在道德上是令人反感的。斯坦福大学医学博士、总统生命伦理委员会成员William Hurlbut最近向委员会提出了一种获取胚胎干细胞的替代方法，他认为这种方法可以规避这一反对意见委员会主席，医学博士利昂·卡斯（Leon Kass）赞成赫尔布特的提议我们认为它是有缺陷的。Hurlbut的建议是基于对携带突变的小鼠胚胎的观察。
The study of human embryonic stem cells is a matter of intense public debate, primarily because derivation of such cells requires the destruction of human blastocysts, a procedure that some find morally objectionable. William Hurlbut, M.D., of Stanford University and a member of the President's Council on Bioethics has recently proposed to the council an alternative way to derive embryonic stem cells that, he argues, circumvents this objection.1 The chair of the council, Leon Kass, M.D., Ph.D., favors Hurlbut's proposal.2 We believe that it is flawed. Hurlbut's proposal is based on the observation that mouse embryos carrying a mutation in . . .