Adherence, reports of benefits, and depression among patients treated with continuous positive airway pressure.
Adherence, reports of benefits, and depression among patients treated with continuous positive airway pressure.
复制标题
持续气道正压治疗患者的依从性、获益报告和抑郁情况。
DOI：
10.1097/psy.0b013e318068b2f7
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发表时间：
2007
影响因子：
3.3
通讯作者：
Stepanski,EdwardJ
中科院分区：
文献类型：
--
作者：
Wells,RachelD;Freedland,KennethE;Carney,RobertM;Duntley,StephenP;Stepanski,EdwardJ
目的：研究报告的阻塞性睡眠呼吸暂停（OSA）症状改善、基线抑郁症状或多导睡眠图测量的睡眠参数是否与持续气道正压通气（CPAP）依从性相关。CPAP是治疗OSA的有效方法。对CPAP治疗的低依从性是常见的，并且了解甚少。抑郁症和缺乏感知的好处，从CPAP是可能的原因低adherence.Methods：78例患者在睡眠医学中心评估OSA同意参加这项研究，54例患者完成了所有的研究评估。在多导睡眠图评估之前，进行Beck抑郁量表（BDI）和睡眠功能结果问卷（FOSQ）。CPAP设备中嵌入的卡以电子方式记录依从性。BDI和FOSQ的管理1至2个月后，基线measurements.Results：基线抑郁症状与平均持续时间的CPAP使用每晚。据报道，阻塞性睡眠呼吸暂停症状的改善与持续气道正压通气的依从性呈正相关。CPAP治疗后抑郁症状的改善与OSA症状的改善呈显著正相关。多导睡眠图测量的变量不能预测白天OSA症状或CPAP依从性的改善。事后分析显示，那些基础呼吸暂停低通气指数（AHI）在40 ~ 80之间的患者比AHI 80的患者有更多的症状改善< 40 or>。结论：CPAP依从性最高的患者也报告了OSA症状的最大改善。CPAP治疗后继续出现OSA症状的患者在CPAP治疗后也倾向于出现更多的抑郁症状。
Objectives:To examine if reported obstructive sleep apnea (OSA) symptom improvement, baseline depressive symptoms, or polysomnographically measured sleep parameters are associated with adherence to continuous positive airway pressure (CPAP). CPAP is a highly effective treatment for OSA. Low adherence to CPAP therapy is common and poorly understood. Depression and lack of perceived benefits from CPAP are possible reasons for low adherence.Methods:Seventy-eight patients evaluated for OSA at a sleep medicine center agreed to participate in the study; 54 patients completed all study assessments. The Beck Depression Inventory (BDI) and the functional outcomes of sleep questionnaire (FOSQ) were administered before polysomnographic evaluation. A card embedded in the CPAP device electronically recorded adherence. The BDI and FOSQ were administered 1 to 2 months after the baseline measurements were obtained.Results:Baseline depressive symptoms were not correlated with mean duration of CPAP use per night. Reported improvements in OSA symptoms were correlated positively with CPAP adherence. There were significant positive correlations between improvement in depressive symptoms and OSA symptoms after initiation of CPAP therapy. The polysomnographic variables measured did not predict improvement in daytime OSA symptoms or CPAP adherence. Post hoc analyses suggested that those individuals with baseline Apnea Hypopnea Index (AHI) between 40 and 80 experienced more symptom improvement than those with AHI< 40 or> 80.Conclusions:Patients with the greatest level of CPAP adherence also reported the greatest improvement in OSA symptoms. Patients who continued to experience OSA symptoms after CPAP treatment also tended to have more depressive symptoms after CPAP treatment.