Benign paroxysmal positional vertigo in older women may be related to osteoporosis and osteopenia
Benign paroxysmal positional vertigo in older women may be related to osteoporosis and osteopenia
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DOI：
10.1177/000348940311201010
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发表时间：
2003-10-01
影响因子：
1.4
通讯作者：
Häusler, R
中科院分区：
文献类型：
--
作者：
Vibert, D;Kompis, M;Häusler, R
良性阵发性位置性眩晕(BPPV)，即所谓的胆管结石和丘状结石，通常发生在头部创伤或病毒性前庭神经炎之后。在许多情况下，病因仍不清楚，而且通常会影响50岁以上的女性。这项工作的目的是研究BPPV与骨量减少或骨质疏松症的可能关系。32名妇女，年龄从50岁到85岁(中位数年龄)。69岁)，患有BPPV且无其他耳神经科病史。骨量减少或骨质疏松的诊断是通过脊柱和髋部双X射线骨密度仪(T-Score)进行的骨密度测量来确认的。单侧26例，双侧6例。我们的结果显示，在32例BPPV患者中，有24例(75%)出现骨量减少或骨质疏松。将3个年龄组的T值与83名健康女性的T值进行比较。在所有组中，BPPV患者的T-Score显著较低(p<；.026)。可能的病理生理学机制被讨论，以解释BPPV与骨量减少或骨质疏松的明显相关性。
Benign paroxysmal positional vertigo (BPPV), so-called canalolithiasis and cupulolithiasis, usually occurs after head trauma or viral vestibular neuritis. In many cases, the cause remains obscure, and it often affects women more than 50 years old. The goal of this work was to study a possible relationship between BPPV and osteopenia or osteoporosis. Thirty-two women, whose ages ranged from 50 to 85 years (median age. 69 years), who had BPPV and were free of any other otoneurologic history, were selected. The diagnosis of osteopenia or osteoporosis was confirmed by a bone mineral density measurement made with dual x-ray absorptiometry Of spine and hip (T-score). The BPPV was unilateral in 26 patients and bilateral in 6 patients. Our results showed osteopenia or osteoporosis in 24 of the 32 patients (75%) with BPPV. The T-scores were compared in 3 age groups to those of 83 healthy women. The patients with BPPV had a significantly lower (p < .026) T-score in all groups. Possible pathophysiological mechanisms are discussed to explain the apparent correlation between BPPV and osteopenia or osteoporosis.