Harpagoside variation is positively correlated with temperature in Scrophularia ningpoensis Hemsl.
Harpagoside variation is positively correlated with temperature in Scrophularia ningpoensis Hemsl.
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DOI：
10.1021/jf104702u
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发表时间：
2011-03
影响因子：
6.1
通讯作者：
Shuting Yang;Jinghui Li;Yunpeng Zhao;Binlong Chen;C. Fu
中科院分区：
文献类型：
--
作者：
Shuting Yang;Jinghui Li;Yunpeng Zhao;Binlong Chen;C. Fu
玄参Hemsl.是一种重要的中药材，已有1000多年的驯化历史。宁波沙棘响应环境梯度的植物化学变化仍然是一个具有实践和理论意义的有吸引力的课题。本研究通过HPLC指纹图谱测定了宁波沙参的四种主要生物活性成分，即哈帕戈苷、安茅苷C、类叶升麻苷和肉桂酸，探讨其与气候、地理和土壤因素的相关性。目前的数据证实了五个产区之间植物化学分化的大致三组模式，即浙江种群（ZJ）、湖北种群（HB）以及重庆、湖南和陕西的其余三个种群（CQ、HN和SX）。哈巴果苷是宁波沙丁鱼的主要生物活性化合物，对植物化学分化贡献最大，与月平均气温和年平均气温呈显着正相关，与海拔和纬度呈负相关。结论是哈帕戈苷的变化与温度的环境变化呈强正相关。
Scrophularia ningpoensis Hemsl. is an important Chinese medicinal herb with a history of domestication of over 1000 years. Phytochemical variation of S. ningpoensis in response to environmental gradients remains an attractive topic with both practiceal and theoretical significances. In the current study, HPLC fingerprinting and four major bioactive compounds of S. ningpoensis, that is, harpagoside, angroside C, acteoside, and cinnamic acid, were determined to explore its correlations with climatic, geographic, and soil factors. The present data confirmed the approximate three-group pattern of phytochemical differentiation among the five production regions, the population of Zhejiang (ZJ), the population of Hubei (HB), and the rest three populations of Chongqing, Hunan, and Shaanxi (CQ, HN, and SX). Harpagoside, the dominant bioactive compound of S. ningpoensis, contributed most to the phytochemical differentiation and displayed a significant positive correlation with monthly and annual average temperature and negative correlations with altitude and latitude. It was concluded that harpagoside variation was strongly positively correlated with environmental changes of temperature.