Myosin V walks hand-over-hand: Single fluorophore imaging with 1.5-nm localization
Myosin V walks hand-over-hand: Single fluorophore imaging with 1.5-nm localization
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DOI：
10.1126/science.1084398
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发表时间：
2003-06-27
期刊：
影响因子：
56.9
通讯作者：
Selvin, PR
中科院分区：
文献类型：
--
作者：
Yildiz, A;Forkey, JN;Selvin, PR
肌球蛋白V是一个二聚体分子马达，它能驱动肌动蛋白的前体，每水解一个三磷酸腺苷，其质心移动约37纳米。我们在轻链结构域的不同位置用单个荧光团标记肌球蛋白V，并测量步长，标准偏差为
Myosin V is a dimeric molecular motor that moves processively on actin, with the center of mass moving similar to37 nanometers for each adenosine triphosphate hydrolyzed. We have labeled myosin V with a single fluorophore at different positions in the light-chain domain and measured the step size with a standard deviation of