Benefits of sinogram-affirmed iterative reconstruction in 0.4 mSv ultra-low-dose CT of the upper abdomen following transarterial chemoembolisation: comparison to low-dose and standard-dose CT and filtered back projection technique
Benefits of sinogram-affirmed iterative reconstruction in 0.4 mSv ultra-low-dose CT of the upper abdomen following transarterial chemoembolisation: comparison to low-dose and standard-dose CT and filtered back projection technique
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DOI：
10.1016/j.crad.2015.10.001
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发表时间：
2016-01-01
影响因子：
2.6
通讯作者：
Beeres, M.
中科院分区：
文献类型：
--
作者：
Bodelle, B.;Isler, S.;Beeres, M.
目的：评价不同管道电流下经动脉化疗栓塞（TACE）后上腹部计算机断层扫描（CT）中，脑电图确认迭代重建（SIR）与滤波反投影（FBP）的优势。材料和方法：该研究已获得机构审查委员会的批准。所有患者均获得书面知情同意。采用不同的管电流进行tace后CT，每组40例（平均年龄：60 +/- 12岁，范围：23-85岁，性别：女性70例，男性90例）。用标准FBP和5种不同的SIR强度重建数据。图像质量是由两位读者按照五分制独立评定的。使用Kruskal-Wallis试验，在一个剂量内单独比较高（脂肪与肝脏）和低（肝脏与脂肪）的噪声对比比（cnr），以确定最佳强度（S1-S5），并在不同剂量之间进行个体间比较，以确定减少剂量的可能性。结果：主观图像质量和客观CNR分析是一致的：个体内，SIR显著(p
AIM: To evaluate the advantage of sinogram-affirmed iterative reconstruction (SIR) compared to filtered back projection (FBP) in upper abdomen computed tomography (CT) after transarterial chemoembolisation (TACE) at different tube currents.MATERIALS AND METHODS: The study was approved by the institutional review board. Written informed consent was obtained from all patients. Post-TACE CT was performed with different tube currents successively varied in four steps (180, 90, 45 and 23 mAs) with 40 patients per group (mean age: 60 +/- 12 years, range: 23-85 years, sex: 70 female, 90 male). The data were reconstructed with standard FBP and five different SIR strengths. Image quality was independently rated by two readers on a five-point scale. High (Lipiodol-to-liver) as well as low (liver-to-fat) contrast-to-noise ratios (CNRs) were intra-individually compared within one dose to determine the optimal strength (S1-S5) and inter-individually between different doses to determine the possibility of dose reduction using the Kruskal-Wallis test.RESULTS: Subjective image quality and objective CNR analysis were concordant: intra-individually, SIR was significantly (p