Modelling binary data from a three-period cross-over trial.
Modelling binary data from a three-period cross-over trial.
复制标题
对三期交叉试验的二进制数据进行建模。
DOI：
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发表时间：
1987
影响因子：
2
通讯作者：
Michael G. Kenward
中科院分区：
文献类型：
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作者：
Byron Jones;Michael G. Kenward
描述了一种分析来自三处理、三阶段交叉试验的二进制数据的新方法。该方法基于对数线性模型并反映连续数据的分析。它是我们最近引入的方法的扩展，用于分析来自两次治疗、两期交叉试验的二进制数据。我们使用一项试验的数据来说明我们的方法，该试验比较了两种镇痛药和安慰剂对缓解原发性痛经的作用。
A new method of analysing binary data from a three-treatment, three-period cross-over trial is described. This method is based on a log-linear model and mirrors the analysis of continuous data. It is an extension of the method we introduced recently for the analysis of binary data from a two-treatment, two-period cross-over trial. We illustrate our method using data from a trial which compared two analgesics and a placebo for the relief of primary dysmenorrhea.