Juvenile myoclonic epilepsy: A clinical and sleep EEG study
Juvenile myoclonic epilepsy: A clinical and sleep EEG study
复制标题
DOI：
10.1053/seiz.2001.0522
复制
发表时间：
2001-07-01
影响因子：
3
通讯作者：
Maheshwari, D
中科院分区：
文献类型：
--
作者：
Dhanuka, AK;Jain, BK;Maheshwari, D
青少年肌阵挛性癫痫（JME）的特征是醒来时肌阵挛抽搐，全身性强直-阵挛性发作（GTCS），并且在超过三分之一的病例中伴有失神发作。本文对15例青少年肌阵挛性癫痫患者的临床特征、脑电图和睡眠脑电图进行了研究。由于各种原因，WE的诊断有延迟（平均3.5年）。睡眠不足是引发癫痫发作最常见的诱发因素，其次是疲劳。73.33%的病例常规脑电图异常，6.66%的病例有误导。睡眠脑电图异常的病例100%有广泛性尖峰、多尖峰和慢波放电。睡眠脑电图放电率通常在过渡阶段（即从睡眠到觉醒阶段）显著增加，我们认为这是在适当的临床环境下的一个具体发现。睡眠脑电图是诊断JME的一种更敏感、更特异的工具，而常规清醒脑电图可能会遗漏或误导JME。(C) 2001东亚贸易有限公司
Juvenile myoclonic epilepsy (JME) is characterized by myoclonic jerks on awakening, generalized tonic-clonic seizures (GTCS) and is associated with absence seizures in more than one third of cases. Fifteen patients with juvenile myoclonic epilepsy were studied with regard to their clinical profile, EEG data and sleep EEG findings. There was a delay in the diagnosis of WE (mean of 3.5 years) due to various reasons. Sleep deprivation was the most common precipitating factor for triggering seizures, followed by fatigue. Routine EEGs were abnormal in 73.33% of cases only and had misleading findings in 6.66%. Sleep EEGs were abnormal in 100% of cases with generalized spikes, polyspikes and slow wave discharges. Discharge rates on sleep EEGs typically increased significantly during the transition phase (i.e. the asleep to awakening stage) and we consider this to be a specific finding in appropriate clinical setting. Sleep EEGs are a more sensitive and specific tool for the diagnosis of JME while routine awake EEGs may miss or mislead. (C) 2001 BEA Trading Ltd.